Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230100747
Funding Status
Active
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Funded Activity Summary
Sperm ciliary gating and midpiece formation – a novel player and process. We have identified CCDC112 an essential player in mammalian sperm tail development and male fertility. This project aims to define the role of CCDC112 in 1) the formation of the core to the sperm tail, the axoneme, and 2) the packaging of mitochondria into the midpiece. Within this Discovery Project we will define the mechanism(s) of CCDC112 functions and the consequences of its dysfunction. Insights from this grant will be of significance to fertility across mammals and may ultimately benefit the selection of highly fertile males within the agricultural sector.Funded Activity Details
Start Date: 2023
End Date: 12-2025
Funding Scheme: Discovery Projects
Funding Amount: $616,065.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Animal developmental and reproductive biology | Reproduction | Reproductive medicine | Animal reproduction and breeding
ANZSRC Socio-Economic Objective (SEO)
