Discovery Projects - Grant ID: DP200103734

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP200103734

Funding Status
Closed

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Funded Activity Summary

Genetic Basis of Variable Expression of Glycan Xeno-Autoantigens by Cattle. Meat and dairy products from cattle contain sugar structures (glycans) that are not made by humans. These structures can be recognised by the immune system and lead to allergic reactions, inflammation and potentially cancer. These non-human structures are called xeno-autoantigens or XAs. We have discovered individual cattle that do not produce one of these XAs. We will study the gene required to make XA in the XA-free cattle to find the underlying mutation. The same approach will be used to look for natural XA-free individuals in other food species. This knowledge may enable us to create a test to facilitate the natural breeding of non-GMO, XA-free livestock to benefit Australian primary producers and provide safer food for consumers.

Funded Activity Details

Start Date: 2020

End Date: 12-2022

Funding Scheme: Discovery Projects

Funding Amount: $480,234.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Animal Breeding | Molecular Evolution | Genetics

ANZSRC Socio-Economic Objective (SEO)

Beef Cattle | Dairy Cattle | Food Safety |

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