Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP150100539
Funding Status
Closed
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Funded Activity Summary
Unravelling the mechanism of vesicular docking in neurosecretory cells. The fusion of secretory vesicles (SVs) by exocytosis underpins neuronal and hormonal communication. The aim of this project is to unravel all the steps bringing these vesicles to the plasma membrane where they dock. Specifically, we aim to unravel the role for the cytoskeleton in creating an interface where SV confinement leads to the appropriate pairing of molecules mediating the fusion between the vesicles and the plasma membrane. Unravelling these novel molecular mechanisms is essential for our understanding of neuronal function in the healthy nervous and hormonal systems.Funded Activity Details
Start Date: 2015
End Date: 12-2018
Funding Scheme: Discovery Projects
Funding Amount: $434,500.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biochemistry and Cell Biology | Cell Neurochemistry
