Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP170101358
Funding Status
Closed
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Funded Activity Summary
How calcium makes the heart grow. This project aims to develop a mathematical model of calcium signalling in heart cells to understand how calcium makes the heart grow. Our hearts grow to adapt to long-term changes, such as during development and in pregnancy or heart disease. Biochemical reactions involving calcium control the growth of heart cells and heart cells also use calcium signalling to trigger contraction with each beat. How calcium controls the heartbeat and regulates cell growth is unknown. This project will develop a new mathematical model of calcium signalling in heart cells to understand important cellular adaption processes. This knowledge will lead to the ability to independently control cellular pathways mediated by calcium, opening new avenues in biotechnology and biomedicine.Funded Activity Details
Start Date: 02-2017
End Date: 06-2020
Funding Scheme: Discovery Projects
Funding Amount: $316,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biological Mathematics | Applied Mathematics |
