Website
https://dataportal.arc.gov.au/NCGP/API/grants/DP0451224
Funding Status
Closed
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Funded Activity Summary
Elucidating the mechanisms by which Scribble, Discs Large and Lethal Giant Larvae regulate epithelial polarity. Discs Large (Dlg) and Scribble are proteins that regulate cell shape by concentrating at particular regions within the cell and recruiting other proteins to that region. It is thought that the two proteins interact with each other, and with other proteins involved in protein trafficking and cell architecture, but it is not known how these events coordinate to produce a net outcome on cell shape. To answer these questions, the dynamic events involved in localization of Dlg, Scribble, and associated proteins will be determined, in mammalian cells and in whole organs of the vinegar fly.Funded Activity Details
Start Date: 01-2004
End Date: 12-2007
Funding Scheme: Discovery Projects
Funding Amount: $290,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Instruments And Techniques | Quantum Optics And Lasers
