Discovery Projects - Grant ID: DP240101500

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP240101500

Funding Status
Active

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Funded Activity Summary

New biocatalysts for selective chemical oxidations under extreme conditions. This project will identify and design new enzyme biocatalysts which function under extreme conditions such as elevated temperature and high concentrations of peroxides. These enzymes will be sourced from microorganisms which are located in extreme biological environments e.g. hot springs (the so-called extremophiles). The expected outcome of this project are the identification of robust enzymes which can catalyse selective oxidation reactions in complex organic molecules, such as steroids. The new biocatalysts developed in this project will have significant benefit in the development of new routes to access bespoke molecules of value in fine chemical synthesis and drug development.

Funded Activity Details

Start Date: 2024

End Date: 12-2026

Funding Scheme: Discovery Projects

Funding Amount: $781,608.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinorganic chemistry | Biocatalysis and enzyme technology | Structural biology (incl. macromolecular modelling) | Industrial biotechnology

ANZSRC Socio-Economic Objective (SEO)

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