Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP170101609
Funding Status
Closed
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Funded Activity Summary
Kruppel-like factors and the methylome. This project aims to test the hypothesis that the KLF/SP family of transcription factors work in part via dynamic interactions with methylated cytosine nucleotides in DNA. This is fundamental to their function as pioneer factors in reprograming and their ability to co-ordinate differentiation and organogenesis. Conversely, dynamic changes in methylation status engage or disengage new regulatory elements in the genome via recruitment of KLF/SP family proteins as specific effectors. This project will address a new paradigm in genetics that is likely to underpin development.Funded Activity Details
Start Date: 09-2017
End Date: 09-2020
Funding Scheme: Discovery Projects
Funding Amount: $665,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Developmental Genetics (incl. Sex Determination) | Epigenetics (incl. Genome Methylation and Epigenomics) | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) | Genetics
