Discovery Projects - Grant ID: DP200103637

Funding Activity

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Funded Activity Summary

Elucidating the mechanisms of mitochondrial DNA escape. The human body is powered by mitochondria, microscopic components of living cells that make the energy they need to function. Mitochondrial damage is linked to a wide spectrum of human diseases, from devastating syndromic illnesses to neurodegeneration and autoimmunity. This project is focused on 1) how stresses such as cancer therapy or infection cause mitochondrial damage, and 2) understanding the biological processes that are triggered inside the cell as it tries to recover. It will give a much greater understanding of mitochondrial damage at the microscopic level, and has the potential to unlock new avenues of investigation into the causes of inflammatory and immune disorders.

Funded Activity Details

Start Date: 12-2020

End Date: 06-2025

Funding Scheme: Discovery Projects

Funding Amount: $530,000.00

Funder: Australian Research Council