Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0452405
Funding Status
Closed
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Funded Activity Summary
Imaging of properties of coherent elastic light scattering from turbid biological media. Imaging with coherent, elastically-scattered light for visualisation of thick-tissue morphology in vivo, or of cells buried deep in a turbid medium, remains a major challenge. We adopt an alternative approach of imaging of properties of light scattering based on regarding cellular tissue as a spatially-varying refractive-index continuum which encodes scattered light. We propose new methodologies to infer tissue state and morphology indirectly based on phase delay, speckle, and angle-resolved scattering. We will break new ground in correlating the structure and function of in situ epithelial tissue and cells to light scattering enabling, e.g., the detection of mitosis and apoptosis in cells buried in thick, turbid media, and of cancers and precancers in vivo.Funded Activity Details
Start Date: 02-2004
End Date: 12-2007
Funding Scheme: Discovery Projects
Funding Amount: $375,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Communications Technologies | Optics And Opto-Electronic Physics | Instruments And Techniques | Optical And Photonic Systems
ANZSRC Socio-Economic Objective (SEO)
Industrial instrumentation | Medical instrumentation | Cancer and related disorders |
