ARC Future Fellowships - Grant ID: FT140101152

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/FT140101152

Funding Status
Closed

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Funded Activity Summary

Imaging-based fluid-structure interaction modelling of carotid atherosclerotic plaque. This project aims to combine computational modelling, magnetic resonance imaging (MRI), mechanical measurement and pathological analysis to investigate carotid plaque progression, and quantify the critical blood flow and plaque stress/strain conditions under which plaque rupture is likely to occur. MRI-based 3D computational models with multi-component plaque structures and their interaction with blood flow will be developed and solved numerically to identify suitable plaque rupture risk indicators. Mechanical properties of plaque components will be measured ex-vivo and fibre orientation-based constitutive rules will be developed. This project aims to lead to quantitative understandings of plaque progression and rupture.

Funded Activity Details

Start Date: 05-2015

End Date: 12-2019

Funding Scheme: ARC Future Fellowships

Funding Amount: $769,896.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomechanical Engineering | Biomedical Engineering | Numerical Modelling and Mechanical Characterisation

ANZSRC Socio-Economic Objective (SEO)

Cardiovascular System and Diseases | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

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