Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP190103525
Funding Status
Closed
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Funded Activity Summary
Defining how serotonin regulates gut motility. This project aims to deepen knowledge of gastrointestinal physiology, and reveal the mechanisms by which the major gastrointestinal signalling molecule, serotonin, regulates gut peristalsis. Almost all of the serotonin in our body is made in the gastrointestinal tract where it controls many functions, including how our gut wall contracts during peristalsis. Proper control of gut peristalsis and the transit of material through our bowel is important for our health. This project expects to define how serotonin controls peristalsis, where in the bowel this serotonin comes from, how serotonin communicates with the nervous system in our gastrointestinal tract, and how the cells that synthesise gut serotonin respond to contraction to trigger the secretion of serotonin.Funded Activity Details
Start Date: 06-2019
End Date: 06-2022
Funding Scheme: Discovery Projects
Funding Amount: $529,290.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Animal Physiology - Cell | Animal Physiology - Systems | Gastroenterology and Hepatology | Physiology
