Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0881071
Funding Status
Closed
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Funded Activity Summary
Functional analysis of Bacillus thuringiensis crystal toxins. Pore-forming toxins, such as anthrax, hemolysin, cholera and diphtheria toxins, are among the most virulent microbial toxins, posing a threat to humans and lifestock. We are using a novel functional approach to test possible lectin and antimicrobial peptide functions of a typical and economically important pore-forming toxin, the crystal endotoxin from Bacillus thuringiensis, to examine why toxicity of the lectin-containing toxin is restricted to invertebrates only, while the amphipathic peptide alone is also toxic to many vertebrate cells. The outcome of these experiments has important implications for the sustainable use of biopesticides and for the prevention and containment of infectious diseases.Funded Activity Details
Start Date: 2008
End Date: 12-2013
Funding Scheme: Discovery Projects
Funding Amount: $255,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Invertebrate Biology | Microbial Ecology | Plant Protection (Pests, Diseases And Weeds) | Crop and Pasture Production
ANZSRC Socio-Economic Objective (SEO)
Cotton | Crop and animal protection chemicals | Biological sciences |
