Website
http://dataportal.arc.gov.au/NCGP/API/grants/FT130100472
Funding Status
Closed
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Funded Activity Summary
Trapped Ion Imaging for Biomolecular Dynamics. The functionality of large biological molecules is driven by their chemical composition and the folded shape of their active form. The higher-order structure and dynamics of nucleic acids, proteins, carbohydrates, and lipids drives the chemistry of life. Combining single molecule microscopy and trapped ion mass spectroscopy will develop a new tool for precision measurements of higher-order folding dynamics in large biomolecules. Optical techniques including Förster resonance energy transfer and super-resolution imaging can register changes in shape down to the nanometer scale. The uniquely adaptable ion trap environment enables manipulation of the surrounding solvent cage, temperature, and net charge down to the single quantum level.Funded Activity Details
Start Date: 2014
End Date: 06-2018
Funding Scheme: ARC Future Fellowships
Funding Amount: $754,820.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Atomic, Molecular, Nuclear, Particle and Plasma Physics | Optical Properties of Materials | Classical and Physical Optics | Atomic and Molecular Physics
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Biological Sciences |
