Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP0665446
Funding Status
Closed
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Funded Activity Summary
Zinc finger domains as scaffolds for protein engineering. While great advances have been made in pharmaceutical design and discovery, it is clear that new types of drugs are needed for the better management of a wide range of diseases (e.g. cancers, autoimmune diseases, viral infections). Many of these diseases arise from inappropriate interactions between intracellular biological macromolecules. My aim is to develop a range of novel therapeutic proteins based on naturally existing zinc-binding protein domains with the goal of selectively blocking these inappropriate interactions. Additionally, these engineered proteins have potential uses as biochemical tools such as to help delineate the functions of natural proteins with no known functions.Funded Activity Details
Start Date: 01-2006
End Date: 11-2008
Funding Scheme: Discovery Projects
Funding Amount: $288,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Genetic Engineering And Enzyme Technology | Medical Biochemistry and Metabolomics | Medical Biochemistry: Proteins And Peptides |
