Discovery Projects - Grant ID: DP0453243

Funding Activity

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Funded Activity Summary

Genetic variation of transcriptional control. Genetic variation is a key cause phenotype differences in humans, animals, and plants and so of great economic importance. Despite its proven importance to human diseases, ?quantitative? variation in the amount of gene expression rather than ?qualitative? protein sequence changes, has not been systematically studied. We have developed a powerful method to identify genetic causes of quantitative variation using crosses of inbred mice in conjunction with microarray techniques to analyse expression of thousands of genes simultaneously. These studies will be extended to humans and be significant to wide areas of biological and commercial activity.

Funded Activity Details

Start Date: 2004

End Date: 12-2006

Funding Scheme: Discovery Projects

Funding Amount: $225,000.00

Funder: Australian Research Council