Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP170102102
Funding Status
Closed
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Funded Activity Summary
Molecular insights into bacterial metal ion homeostasis and toxicity. This project aims to measure bacterial cellular metal concentrations, elucidate mechanisms cells use to adapt to changing extracellular metal concentrations, and reveal the molecular targets of metal toxicity. Metal ions are essential to all forms of life, and half of all proteins use metal ions for cellular chemical processes. However, how cells precisely balance sufficient metal ions for essential cellular chemistry without accumulating a toxic excess (metal homeostasis) is poorly understood. Discovering the roles of metal ions in bacterial cells will be key to defining the chemical biology of living systems and will provide information essential to understanding how microbes adapt to changing environments.Funded Activity Details
Start Date: 2017
End Date: 12-2020
Funding Scheme: Discovery Projects
Funding Amount: $605,500.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Receptors and Membrane Biology | Microbiology | Bacteriology
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology |
