Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP200101248
Funding Status
Active
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Funded Activity Summary
A microfluidic approach to study the mechanobiology of ageing blood vessels. This project aims to study the effect of the stiffening of ageing arteries in endothelial cells. It explores the changes that occur in endothelial cells using a unique microfluidic technology with tuneable wall stiffness to mimic the biophysical and biochemical properties of ageing arteries. The expected outcome is the identification of the cellular mechanisms that control endothelial responses to arterial stiffening. This should provide the fundamental knowledge required to assist in the development of new therapies to tackle age-related conditions such as cardiovascular disease and dementia.Funded Activity Details
Start Date: 06-2020
End Date: 12-2024
Funding Scheme: Discovery Projects
Funding Amount: $480,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Human Biophysics | Receptors and Membrane Biology | Medical Physiology
