Molecular memory: how DNA methylation contributes to spatial memory

Funding Activity

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Funded Activity Summary

The brain stores memories that can last a lifetime and our memory is core to mental health, but we still do not know how memories are stored. Here we explore a radical new theory that memory storage involves chemical modification of the DNA molecule - DNA-methylation. We will examine how memory changes patterns of DNA-methylation, and how modifying DNA-methylation can change memory. Our work will examine the biochemical basis of memory, and will inspire new strategies to treat memory disorders.

Funded Activity Details

Start Date: 2010

End Date: 2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $482,842.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics)

ANZSRC Socio-Economic Objective (SEO)

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