Discovery Projects - Grant ID: DP150102437

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP150102437

Funding Status
Closed

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Funded Activity Summary

Using viral inhibitors to understand the regualtion of apoptosis. Apoptosis is a form of cell death that is critical for the development and well-being of multicellular organisms. The activity of Bak or Bax, two members of the Bcl-2 family, are essential for apoptosis to proceed, but how the activity of these two proteins is regulated is unclear. Many viruses encode inhibitors of apoptosis and the project will make use of two novel viral inhibitors that specifically target Bak. The project aims to determine how the Bak inhibitors function and to provide valuable insights into the normal mechanisms regulating Bak activity.

Funded Activity Details

Start Date: 2015

End Date: 12-2017

Funding Scheme: Discovery Projects

Funding Amount: $251,500.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Virology | Biochemistry and Cell Biology | Signal Transduction | Cell Development, Proliferation and Death |

ANZSRC Socio-Economic Objective (SEO)

Cancer and Related Disorders | Infectious Diseases

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