Harnessing the 'omics revolution to investigate drug response and resistance mechanisms in Giardia duodenalis. This international research project will harness cutting-edge technologies to explore how Giardia, a major global cause of diarrhoeal illness in humans, responds to and becomes resistant to key anti-giardial drugs, providing valuable information for drug preservation and development.
Characterization of the dark metabolome of eukaryotic cells. The project aims to investigate the full metabolic potential of a group of eukaryotic organisms using advanced analytical and computational techniques. It will identify novel metabolites and enzyme activities that are currently not predicted from genome annotations. Expected outcomes of the project include the delineation of new metabolic processes that are common to all eukaryotes, the characterization of new enzymes families, and the ....Characterization of the dark metabolome of eukaryotic cells. The project aims to investigate the full metabolic potential of a group of eukaryotic organisms using advanced analytical and computational techniques. It will identify novel metabolites and enzyme activities that are currently not predicted from genome annotations. Expected outcomes of the project include the delineation of new metabolic processes that are common to all eukaryotes, the characterization of new enzymes families, and the generation of comprehensive metabolic databases. An improved understanding of cellular metabolism will provide direct benefits in biotechnology, food production, environmental monitoring and the diagnosis and treatment of human metabolic and infectious diseases. Read moreRead less