Time- and Temperature-Dependence of the Fluid Transport Properties, Strength and Mechanical Behaviour of Crustal Faults - An Experimental and Modelling Study. High temperature rock deformation experiments will be performed in conjunction with high resolution, computer-aided x-ray microtomography to determine time-dependent and temperature-dependent effects on fluid transport properties, strength and mechanical behaviour during slip and interseismic healing of simulated fault rocks in hydrotherma ....Time- and Temperature-Dependence of the Fluid Transport Properties, Strength and Mechanical Behaviour of Crustal Faults - An Experimental and Modelling Study. High temperature rock deformation experiments will be performed in conjunction with high resolution, computer-aided x-ray microtomography to determine time-dependent and temperature-dependent effects on fluid transport properties, strength and mechanical behaviour during slip and interseismic healing of simulated fault rocks in hydrothermal environments. The results will be used with cellular automaton modelling approaches to develop a quantitative understanding of how coupling between fluid flow and rock deformation controls earthquake rupture and fluid migration in fault networks in the continental seismogenic regime. This work will provide new understanding of triggers for earthquake nucleation and controls on localisation of ore deposits.Read moreRead less
Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Platinum deposit genesis: A new way of thinking. Platinum is becoming increasingly crucial to the high technology sector, and is used particularly in catalytic converters and fuel cells, which serve to minimise or eliminate car exhaust pollution. Greatly expanded resources of this precious metal are needed to help society's transition to a low carbon dioxide (CO2) lifestyle. This project will combine high temperature-pressure experiments with geological field research to greatly improve our unde ....Platinum deposit genesis: A new way of thinking. Platinum is becoming increasingly crucial to the high technology sector, and is used particularly in catalytic converters and fuel cells, which serve to minimise or eliminate car exhaust pollution. Greatly expanded resources of this precious metal are needed to help society's transition to a low carbon dioxide (CO2) lifestyle. This project will combine high temperature-pressure experiments with geological field research to greatly improve our understanding of how platinum ore deposits form and thus where to find them. The outcomes of this project will change mineral exploration strategies in Australia and around the world, and facilitate our progression to a cleaner, greener future.Read moreRead less
Platelet Glycoprotein Proteolysis: Novel Mechanisms And Risk Factors
Funder
National Health and Medical Research Council
Funding Amount
$441,473.00
Summary
Platelets are the richest source of amyloid precursor protein (APP) in the body. Platelet ADAM10 regulates both the expression and function of the major platelet collagen receptor GPVI, and protective APP processing. Coagulation protein Factor X has a role in activation of ADAM10. This activation is disrupted in blood that has been treated with direct oral anticoagulant (DOAC) rivaroxaban. This grant will investigate the implications for people taking rivaroxaban on regulation of APP and GPVI.
The hydrothermal solubility of molybdenum: A LA-ICPMS study of synthetic and natural fluid inclusions. The solubility of molybdenum under magmatic-hydrothermal conditions is essentially unknown. This study will, for the first time, identify the fundamental controls on molybdenum solubility in porphyry systems. This information will provide geologists with basic information on the transport and deposition of this important ore metal. In an allied study, the ore metals; copper, gold and molybdenum ....The hydrothermal solubility of molybdenum: A LA-ICPMS study of synthetic and natural fluid inclusions. The solubility of molybdenum under magmatic-hydrothermal conditions is essentially unknown. This study will, for the first time, identify the fundamental controls on molybdenum solubility in porphyry systems. This information will provide geologists with basic information on the transport and deposition of this important ore metal. In an allied study, the ore metals; copper, gold and molybdenum, will be traced through the Kidston porphyry system, Queensland. This will clarify the processes that lead to ore deposition, which will ultimately allow geologists to more effectively explore for porphyry-type deposits, a major target for Australian mining companies in the Pacific region.Read moreRead less
Plate kinematics to plate dynamics: understanding plate boundary processes at the global scale. This proposal aims to create geodynamic models which can be used a basis for a new, smart resource exploration and extraction industry which uses simulation to help characterize regions where traditional geophysical imaging alone is not able to penetrate. It provides essential scientific underpinnings for
The Australian Computational Earth System Simulator Major National Research Facility (ACcESS).
Solidification, Channel Formation and Thermal Erosion In Lava Flows. This project will elucidate the complex dynamics that control the cooling rates and advance rates of lava flows. It will result in improved hazard assessments for volcanic areas around the world affected by the advance of lava flows, including many Pacific islands and most countries around the Pacific Rim. The project will also provide a quantitative understanding of thermal erosion in lava channels, which will help explain th ....Solidification, Channel Formation and Thermal Erosion In Lava Flows. This project will elucidate the complex dynamics that control the cooling rates and advance rates of lava flows. It will result in improved hazard assessments for volcanic areas around the world affected by the advance of lava flows, including many Pacific islands and most countries around the Pacific Rim. The project will also provide a quantitative understanding of thermal erosion in lava channels, which will help explain the formation and location of major ore deposits of nickel, copper and platinum in Western Australia and elsewhere around the world.Read moreRead less
NUMERICAL MODELS OF PLATE TECTONICS, MANTLE CONVECTION AND SLAB DYNAMICS WITH EVOLVING FAULTS. We plan to develop a method for simulating large-scale
geological structures with a much improved treatment
of tectonic faults in 3D.
Current computer models have sharp geological faults at plate
boundaries represented by broad, blurred zones. New techniques
for modeling cracks in engineering structures will be scaled up to
the whole Earth.
This will help us to understand how the Earth's p ....NUMERICAL MODELS OF PLATE TECTONICS, MANTLE CONVECTION AND SLAB DYNAMICS WITH EVOLVING FAULTS. We plan to develop a method for simulating large-scale
geological structures with a much improved treatment
of tectonic faults in 3D.
Current computer models have sharp geological faults at plate
boundaries represented by broad, blurred zones. New techniques
for modeling cracks in engineering structures will be scaled up to
the whole Earth.
This will help us to understand how the Earth's plates move and
interact now and in the past and how the structure of the continents
arose.
Not only is this intrinsically interesting, it
will also be of immediate practical benefit to geological modelers.Read moreRead less
The Fluid Dynamics of Lava Flows: Silicic Domes and Basaltic Channels. Lava flows surface much of the Earth, Moon and terrestrial planets. This interdisciplinary program will combine laboratory experiments, mathematical analysis, numerical modelling and field observations to elucidate the complex dynamics of lava flows, including the nonlinear coupling of flow with surface solidification and basal melting. The focus will be on lava dome instability, and flow in open channels and tubes. Expected ....The Fluid Dynamics of Lava Flows: Silicic Domes and Basaltic Channels. Lava flows surface much of the Earth, Moon and terrestrial planets. This interdisciplinary program will combine laboratory experiments, mathematical analysis, numerical modelling and field observations to elucidate the complex dynamics of lava flows, including the nonlinear coupling of flow with surface solidification and basal melting. The focus will be on lava dome instability, and flow in open channels and tubes. Expected outcomes include: the ability to predict rates of lava flow cooling and advance, indicators of hazardous lava dome collapse, improved volcanic hazard assessments, explanations of the genesis of world-class magmatic ore deposits, and new interpretations of planetary surface morphologies.Read moreRead less
An experimental exploration of silicate melt therrmodynamics. The chemical properties of magmas are the key to understanding igneous activity in the Earth, and hence the tectonic significance of magmatism, and the mineral resources resulting from past magmatism. The chemistry of magmas is also a determining factor in assessing the hazards associated with volcanic eruptions, including natural inputs into the atmosphere against which anthropogenic inputs causing climate change must be assessed. Th ....An experimental exploration of silicate melt therrmodynamics. The chemical properties of magmas are the key to understanding igneous activity in the Earth, and hence the tectonic significance of magmatism, and the mineral resources resulting from past magmatism. The chemistry of magmas is also a determining factor in assessing the hazards associated with volcanic eruptions, including natural inputs into the atmosphere against which anthropogenic inputs causing climate change must be assessed. This research program will measure experimentally the way different magma compositions affect the solubilites of important volatile and trace-element components in magmas, providing the much-needed fundamental data to model magmatic activity.Read moreRead less