Neutrophil-macrophage Co-operation In The Resolution Of Inflammation
Funder
National Health and Medical Research Council
Funding Amount
$325,854.00
Summary
Failed inflammation resolution is at the core of many diseases and has a significant impact on the progression of cancers and atherosclerosis. Visualising and manipulating inflammation in zebrafish has led to key discoveries. Neutrophil-macrophage interactions may be a key process regulating inflammation resolution, and understanding this process better at a molecular level is likely to identify important pathways that might be manipulated for the benefit of patients with chronic inflammation.