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Exploring the brain mechanisms underlying hyperactivity in Attention-Deficit/Hyperactivity Disorder. Attention-deficit/Hyperactivity Disorder (AD/HD) is the most common psychiatric disorder affecting children, resulting in substantial costs (both human and financial) to the child, their family and Australian society. The outcomes of this project will provide a better foundation for understanding dysfunctional brain mechanisms in AD/HD, which is expected to lead to better diagnosis, treatment, an ....Exploring the brain mechanisms underlying hyperactivity in Attention-Deficit/Hyperactivity Disorder. Attention-deficit/Hyperactivity Disorder (AD/HD) is the most common psychiatric disorder affecting children, resulting in substantial costs (both human and financial) to the child, their family and Australian society. The outcomes of this project will provide a better foundation for understanding dysfunctional brain mechanisms in AD/HD, which is expected to lead to better diagnosis, treatment, and community support. Ultimately this will contribute to a healthy start to life for these children. This project will also demonstrate how an integrated Australian approach can lead the research agenda in both basic neuroscience, at the interface of psychology and physiology, and its applications in health.Read moreRead less
Validation of a New Conceptual Model of ADHD based on Underlying Central Nervous System Dysfunction. ADHD is a debilitating problem that affects 5% of children and approximately half as many adults. ADHD causes substantial problems at school and if untreated, predisposes the individual to increased drug and alcohol use, marital breakdown, criminal prosecution and psychiatric problems in later life. One problem is that we do not fully understand what are the causes of the disorder. This project w ....Validation of a New Conceptual Model of ADHD based on Underlying Central Nervous System Dysfunction. ADHD is a debilitating problem that affects 5% of children and approximately half as many adults. ADHD causes substantial problems at school and if untreated, predisposes the individual to increased drug and alcohol use, marital breakdown, criminal prosecution and psychiatric problems in later life. One problem is that we do not fully understand what are the causes of the disorder. This project will test the validity of several models of brain dysfunction in ADHD which have been influential in the literature, but poorly tested. Through better understanding of the basic underlying problems, more effective intervention can be developed.Read moreRead less
Development of Central Nervous System Functioning in AD/HD: a Longitudinal Study. Attention-Deficit/Hyperactivity Disorder (AD/HD) is a debilitating problem affecting 5% of children. AD/HD causes substantial school problems and predisposes the child to drug and alcohol abuse, marital breakdown, criminal prosecution and psychiatric problems in later life. At present we know very little about the underlying causes of the behavioural changes seen in this disorder. This project will clarify the matu ....Development of Central Nervous System Functioning in AD/HD: a Longitudinal Study. Attention-Deficit/Hyperactivity Disorder (AD/HD) is a debilitating problem affecting 5% of children. AD/HD causes substantial school problems and predisposes the child to drug and alcohol abuse, marital breakdown, criminal prosecution and psychiatric problems in later life. At present we know very little about the underlying causes of the behavioural changes seen in this disorder. This project will clarify the maturational abnormalities in brain function that occur from childhood through to adulthood in this disorder. Better understanding of the normal developmental paths of this disorder will have major clinical benefits as it will allow the development of more optimal treatment plans for these children.Read moreRead less
The role of preferred brain states in perceptual and cognitive processing: New insights into brain dynamics. New insights into brain dynamics will improve our understanding of both normal and atypical functioning. Extending previous work on normals will confirm how innovative Australian approaches can lead the research agenda in basic neuroscience, at the psychology-physiology interface. Testing in AD/HD and elderly populations will clarify dysfunctional brain mechanisms underlying AD/HD, and th ....The role of preferred brain states in perceptual and cognitive processing: New insights into brain dynamics. New insights into brain dynamics will improve our understanding of both normal and atypical functioning. Extending previous work on normals will confirm how innovative Australian approaches can lead the research agenda in basic neuroscience, at the psychology-physiology interface. Testing in AD/HD and elderly populations will clarify dysfunctional brain mechanisms underlying AD/HD, and the cognitive losses in elderly populations (exacerbated by dementia). These results may lead to better diagnosis, treatment, and community understanding of these groups. Also, publications on these target groups will demonstrate internationally the widespread utility of this approach, encouraging further novel applications of basic neuroscience in health.Read moreRead less
Cognitive, behavioural and educational outcomes of fetal antiepileptic drug exposure. The study falls within the National Research Priority of Promoting and Maintaining Good Health, in particular the Priority Goal - A Healthy Start to Life. The research will yield information crucial to our understanding of the effects of fetal AED exposure on cognitive and behavioural development in the significant number of affected Australian children born each year. It will enhance the nation's ability to de ....Cognitive, behavioural and educational outcomes of fetal antiepileptic drug exposure. The study falls within the National Research Priority of Promoting and Maintaining Good Health, in particular the Priority Goal - A Healthy Start to Life. The research will yield information crucial to our understanding of the effects of fetal AED exposure on cognitive and behavioural development in the significant number of affected Australian children born each year. It will enhance the nation's ability to develop strategies for prevention, surveillance and remediation of adverse outcomes in early childhood, thus supporting the Government's National Agenda for Early Childhood initiative. As a consequence educational assistance can be targeted for those children likely to experience difficulties. Read moreRead less