Envisaging Citizenship: Australian Histories and Global Connections. This project aims to investigate the ways that visual images have defined, contested and advanced ideas of Australian citizenship and rights from European settlement to the present. Responding to the lack of a shared mainstream understanding of Australian citizenship, it looks beyond legal definitions to explore cultural and especially visual views of citizenship over time. Through collaboration with museum, media and education ....Envisaging Citizenship: Australian Histories and Global Connections. This project aims to investigate the ways that visual images have defined, contested and advanced ideas of Australian citizenship and rights from European settlement to the present. Responding to the lack of a shared mainstream understanding of Australian citizenship, it looks beyond legal definitions to explore cultural and especially visual views of citizenship over time. Through collaboration with museum, media and education sectors, it will provide a forward-looking and accessible public history, and utilise the potential of images to broaden contemporary debates about citizenship. Expected outcomes include a better public understanding of the pathways to citizenship, and enhanced engagement with Australian values and identity.Read moreRead less
Representation of gender and sexual diversity in Australian film and television. This project aims to investigate the cultural, health and identity impact of gender/sexually-diverse characters, themes and narratives in Australian film and television from 1990 to present. The project expects to generate new knowledge by providing the first comprehensive account of Australian media production’s contribution to sexual minority representation, in the context of its importance for fostering healthy i ....Representation of gender and sexual diversity in Australian film and television. This project aims to investigate the cultural, health and identity impact of gender/sexually-diverse characters, themes and narratives in Australian film and television from 1990 to present. The project expects to generate new knowledge by providing the first comprehensive account of Australian media production’s contribution to sexual minority representation, in the context of its importance for fostering healthy identities, and acceptance of minorities to mainstream audiences in a digital media era. This knowledge will provide significant benefit to the mental health, wellbeing and social harmony for both minority and mainstream Australians and help showcase an important aspect of Australian media inclusivity and diversity in international scholarship.Read moreRead less
Ethics and aesthetics as criteria for innovation: A design research study of biological art and digital architecture. The project will contribute to the goal of promoting innovation in three areas. First, the project will amplify Australia's individual strengths in biological art and digital architecture by creating a network of artists and designers in which each discipline is stimulated by the concerns and practices of the other. Second, the project will explain innovation in such networks, by ....Ethics and aesthetics as criteria for innovation: A design research study of biological art and digital architecture. The project will contribute to the goal of promoting innovation in three areas. First, the project will amplify Australia's individual strengths in biological art and digital architecture by creating a network of artists and designers in which each discipline is stimulated by the concerns and practices of the other. Second, the project will explain innovation in such networks, by identifying activities that lead to innovation. Such an explanation will improve the nation's capacity to promote innovation in targeted fields. Third, the project will test and develop collaboration tools designed to support the activities identified as leading to innovation, as information technology is a primary enabler for operating across such networks.
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Characterisation Of Eurl, A Novel Gene Implicated In The Etiology Of Abnormal Brain Development And Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$597,541.00
Summary
Intellectual disability affects around one per cent of Australians, and can arise from genetic abnormalities during fetal life, such as through abnormal regulation of gene expression. We have identified a novel gene, known as eurl, which controls brain assembly as well as the ability of neurons to form functional connections within the brain. We will investigate how this novel gene controls brain development, and characterise eurl as a potential therapeutic target for learning and memory.
Utilitarian Filmmaking in Australia 1945 - 1980. The project plans to discover, document, analyse and compile a lasting archive of utilitarian filmmaking in Australia. 'Utilitarian' describes client-sponsored, instructional and governmental filmmaking existing outside the conventional theatrical contexts by which cinema is usually defined. Focused on the post-World War Two decades before the proliferation of video in the late 1970s, the project aims to highlight previously-unstudied aspects of t ....Utilitarian Filmmaking in Australia 1945 - 1980. The project plans to discover, document, analyse and compile a lasting archive of utilitarian filmmaking in Australia. 'Utilitarian' describes client-sponsored, instructional and governmental filmmaking existing outside the conventional theatrical contexts by which cinema is usually defined. Focused on the post-World War Two decades before the proliferation of video in the late 1970s, the project aims to highlight previously-unstudied aspects of the media industries. This is designed to deliver new knowledge of the skills and subject matter that sustained filmmaking, communication and education in Australia during a time when conventional scholarship assumes there was almost no significant filmmaking.Read moreRead less
The critical role of kisspeptin/neurokinin/dynorphin (KNDy) neurons in gonadotropin releasing hormone (GnRH) release. The brain controls fertility through the secretion of its primary stimulatory factor, gonadotropin releasing hormone (GnRH). Brain cells producing three key peptide hormones, kisspeptin, neurokin B and dynorphin (termed KNDy cells) are vital for the control of GnRH. This project will detail the role of KNDy cells in puberty and reproduction.
Subcellular recruitment of a RhoA ubiquitination complex by Rnd proteins. This study addresses a novel molecular mechanism through which members of the Rnd family of GTP-binding proteins regulate the morphology and migration of immature nerve cells of the developing nervous system. This study has broad implications for the understanding of cell migration during embryo development, as well as in health and disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561030
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiative ....Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiatives in developmental and cellular biology. This large-scale, high-resolution expression profiling infrastructure is required to maintain international competitiveness and will dramatically improve our gene discovery, functional assessment and understanding of vertebrate development.Read moreRead less
Masterminding Reproduction: Kisspeptin and RFamide-Related Peptide. There are a number of concerning trends in reproductive health. Women are reporting difficulty conceiving and maintaining pregnancies; while sperm count and quality are declining in men. More concerning is the increase in reproductive cancers. Gonadotropin-releasing hormone (GnRH) antagonist and agonist have been used for decades to treat reproductive cancers (such as breast cancer and prostate cancer), infertility and precociou ....Masterminding Reproduction: Kisspeptin and RFamide-Related Peptide. There are a number of concerning trends in reproductive health. Women are reporting difficulty conceiving and maintaining pregnancies; while sperm count and quality are declining in men. More concerning is the increase in reproductive cancers. Gonadotropin-releasing hormone (GnRH) antagonist and agonist have been used for decades to treat reproductive cancers (such as breast cancer and prostate cancer), infertility and precocious puberty. Kisspeptin and RF-related peptide may offer more physiological alternatives to GnRH, without detrimental side effects. We will fully explore these two newly defined and major players in reproduction and provide a physiological framework for their progression to clinical use.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less