Island Perspective: A critical examination into Tasmania's internationally recognised regional identity through the contribution of its contemporary studio furniture, 1970-2003. Contemporary studio furniture in Tasmania has a leading national reputation, and international recognition. This project will investigate the practice of the best of contemporary Tasmanian studio furniture to interpret its social and economic history as a reflection on an island culture. The outcomes will be a consolida ....Island Perspective: A critical examination into Tasmania's internationally recognised regional identity through the contribution of its contemporary studio furniture, 1970-2003. Contemporary studio furniture in Tasmania has a leading national reputation, and international recognition. This project will investigate the practice of the best of contemporary Tasmanian studio furniture to interpret its social and economic history as a reflection on an island culture. The outcomes will be a consolidated body of unique, hitherto undocumented knowledge from the 1970s to the present, which explores identity and place throught the diversity of individual design philosophy and furniture production. The significance of this knowledge will be its contributuon towards a dialogue between political, cultural and environmental positions on an island identity within a global context.Read moreRead less
Does binocular vision training enhance literacy among primary school children with poor reading? One in ten Australian children can not read well despite adequate intelligence and opportunity. This project aims to find out the extent that these reading problems reflect poor binocular vision (the eyes not working well together) and evaluate new treatments.
Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be ....Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be used to: develop interventions that improve learning and educational outcomes; counteract age-related memory decline and enable longer work force participation; develop strategies to circumvent the memory loss caused by brain diseases, or improve the design of computer hardware.Read moreRead less
Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These a ....Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These are significant community issues in both economical and social terms. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest cellular processes associated with aging or disease of the brain, and will provide clues to promoting healthy aging.Read moreRead less
Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to th ....Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or neurodegenerative disease. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest biochemical and cellular processes associated with aging or disease of the brain.Read moreRead less
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less
Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.
The Derwent project: immersive digital media visualisations for the representational problems of complex and remote environments. The Derwent Project will create new ways to visualise the complex natural and cultural history of Tasmania’s Derwent River system. This vast and often inaccessible environment includes Aboriginal and colonial heritage alongside ten hydroelectric developments. Its multiple layers of space and time present new opportunities to synthesise artistic and scientific paradigm ....The Derwent project: immersive digital media visualisations for the representational problems of complex and remote environments. The Derwent Project will create new ways to visualise the complex natural and cultural history of Tasmania’s Derwent River system. This vast and often inaccessible environment includes Aboriginal and colonial heritage alongside ten hydroelectric developments. Its multiple layers of space and time present new opportunities to synthesise artistic and scientific paradigms of representation by drawing on geography, history, and archaeology. The outcome will be innovative forms of immersive time-based digital imaging that evocatively reveal hidden layers of environmental information to both specialist and general audiences.Read moreRead less
Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge mic ....Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge microscopy techniques to visualise whether the endogenous astrocyte protein metallothionein can promote regeneration in the injured nervous system of living zebrafish. The successful outcomes of this project will provide significant insight into understanding how the brain responds to injury.Read moreRead less
Feminist theory meets indigenous art. Aboriginal reconciliation is high on the social and cultural agenda in Australian life. The place of art in this political moment has been critical - the culture of Australian indigenous people has come to international attention, and won recognition, largely through art works. This reflects in many cases a political strategy on the part of indigenous communities to use art to depict their traditional Dreamings, of which the world was ignorant. But underlyin ....Feminist theory meets indigenous art. Aboriginal reconciliation is high on the social and cultural agenda in Australian life. The place of art in this political moment has been critical - the culture of Australian indigenous people has come to international attention, and won recognition, largely through art works. This reflects in many cases a political strategy on the part of indigenous communities to use art to depict their traditional Dreamings, of which the world was ignorant. But underlying this, is the assumption made in Aboriginal philosophies that the art is the knowledge it portrays, which in turn evokes title to land through the law of Dreaming, of belonging to "country". To better understand this negotiation advances debate on issues surrounding reconciliation.Read moreRead less