What is successful public art today?: exploring how contemporary public art and memorial design shapes public engagement, perceptions and behaviour. Much public money is invested in public art and memorials. The research explores critical questions of value: what the public enjoys about such artworks, if and how artworks contribute amenity to public spaces, and whether recent artworks engage effectively with social memory, identity and politics. The research situates local practice within intern ....What is successful public art today?: exploring how contemporary public art and memorial design shapes public engagement, perceptions and behaviour. Much public money is invested in public art and memorials. The research explores critical questions of value: what the public enjoys about such artworks, if and how artworks contribute amenity to public spaces, and whether recent artworks engage effectively with social memory, identity and politics. The research situates local practice within international trends, to inform Australian designers, policymakers, art patrons and public space managers about recent innovations in technology, craft, creativity and critique, so they can create and choose public artworks and memorials which engage with the potentials of contemporary arts practice, the complexities of contemporary culture, and the diversity of social behaviour in public spaces.Read moreRead less
Cinematic Ethics: Exploring Ethical Experience through Film. This project develops a new interdisciplinary framework for understanding cinema’s unique power to evoke ethical experience via audiovisual means. Combining philosophy with film analysis, it moves beyond the prevalent view that cinema merely illustrates moral situations, and challenges the long-held suspicion toward film’s manipulative aesthetic power. This project proposes instead a model of cinematic ethics: an investigation of how c ....Cinematic Ethics: Exploring Ethical Experience through Film. This project develops a new interdisciplinary framework for understanding cinema’s unique power to evoke ethical experience via audiovisual means. Combining philosophy with film analysis, it moves beyond the prevalent view that cinema merely illustrates moral situations, and challenges the long-held suspicion toward film’s manipulative aesthetic power. This project proposes instead a model of cinematic ethics: an investigation of how cinema evokes ethical experience through emotional, cognitive, and aesthetic engagement. This project will advance the emerging interdisciplinary field of film-philosophy by highlighting film’s under-recognised potential to enhance ethical understanding, and thus to promote greater social awareness and intercultural communication.Read moreRead less
Unraveling the role of N-acetyl-aspartate in normal brain function and disease. The purpose of this project is to define the role of the predominating brain chemical N-acetyl-aspartate for normal nerve cell function and as toxic agent causing neurological illness and severe mental health problems. Findings of this research will enhance the design of novel therapies involving pharmacological and genetic treatment.
Modelling the human nervous system with human pluripotent stem cells. The human nervous system is one of the most complex structures evolved to date. In order to understand how it functions, and dysfunctions in a diseased state, it is fundamental to decipher how it develops to generate various neuronal populations that form this elaborate network. Human stem cells provide a valuable source to study such processes. The aim of this project is to use human stem cells to study how early progenitor c ....Modelling the human nervous system with human pluripotent stem cells. The human nervous system is one of the most complex structures evolved to date. In order to understand how it functions, and dysfunctions in a diseased state, it is fundamental to decipher how it develops to generate various neuronal populations that form this elaborate network. Human stem cells provide a valuable source to study such processes. The aim of this project is to use human stem cells to study how early progenitor cell types that structure the nervous system are generated and how their neuronal derivatives form connectivity and functional synapses. The outcome of these studies is that we will establish a cellular model of human neurogenesis that can be utilised to study developmental disease processes.Read moreRead less
Migration and mobility: the question of childhood in Chinese and European cinema since 1945. This project will produce a comparative account of the migrant and mobile child in postwar film, researched in China and Europe. It will contribute deeper knowledge of how childhood has been valued in key societies since 1945, and will bring new energy to international and domestic debates on the status, image and experience of migrant children.
The reformulation of war art as a dialogical interactive narrative. This research uses visualisation technology to explore new ways to communicate and understand the collective experience and personal memories of war. It aims to strengthen Australia's leadership in media arts, facilitating the active participation of defence personnel in the creation of a world-first interactive archive of war stories.
Benefits of blood pressure lowering to combat cardiovascular disease. Stroke and heart attack are the commonest causes of death and adult disability. In Australia, approximately 50,000 people die from cardiovascular disease each year. This project will attempt to prevent stroke/heart attack and to improve quality of life by exploring better management of high blood pressure.
Spatiotemporal signatures of learning in brain reward systems. Learning to strengthen behaviours that secure resources and warrant survival is one of the primary functions of the brain. This Project seeks to establish the rules that govern the integration of learning in brain reward systems by studying how neuronal circuits change their molecular signatures as animals assimilate new knowledge. These studies will combine novel experimental designs to investigate learning with multidisciplinary me ....Spatiotemporal signatures of learning in brain reward systems. Learning to strengthen behaviours that secure resources and warrant survival is one of the primary functions of the brain. This Project seeks to establish the rules that govern the integration of learning in brain reward systems by studying how neuronal circuits change their molecular signatures as animals assimilate new knowledge. These studies will combine novel experimental designs to investigate learning with multidisciplinary methods for mapping, recording and functionalising teaching signals in behaving mice. The outcomes will create a significant shift in our understanding of the neural bases that underlie reward learning, and will critically expand the field by providing a new model of learning integration in brain systems.Read moreRead less
Mapping, recovery and remediation of arm coordination deficits after stroke. Coordination of arm movement is a significant problem after a stroke. This innovative project will underpin new treatments by focusing on what type of stroke causes difficulty in coordinating arm movement, describing the coordination difficulties in detail and investigating mechanisms of recovery and treatment.
Targeting brain lipid homeostasis to treat Alzheimer's disease. Dementia affects approximately 250,000 people in Australia at an estimated cost (in 2002) of $6.6 billion per annum. The major cause of dementia (accounting for approximately 70% of all cases) is Alzheimer's disease (AD); a progressive neurodegenerative illness for which there is no curative or disease-stalling treatment. Due to increases in life expectancy, the incidence of AD is predicted to triple by 2050 unless disease-modifying ....Targeting brain lipid homeostasis to treat Alzheimer's disease. Dementia affects approximately 250,000 people in Australia at an estimated cost (in 2002) of $6.6 billion per annum. The major cause of dementia (accounting for approximately 70% of all cases) is Alzheimer's disease (AD); a progressive neurodegenerative illness for which there is no curative or disease-stalling treatment. Due to increases in life expectancy, the incidence of AD is predicted to triple by 2050 unless disease-modifying treatments are developed. This research program will provide novel realistic pharmaceutical approaches to treat AD. Even if the onset of AD could be delayed by a few years the personal and financial benefits would be enormous. The potential for this research to generate commercially viable Australian intellectual property is also significant.Read moreRead less