Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Art and Human Rights in the Asia-Pacific: The Limits of Tolerance in the Twenty-First Century. The question of human rights is emerging as perhaps the most critical issue of the twenty-first century. This project aims to develop a cross-disciplinary methodology and a set of conceptual frameworks for analysing the interactions between contemporary art and global discourses on human rights in the Asia-Pacific. In the process we address the debate on universality versus cultural specificity in rel ....Art and Human Rights in the Asia-Pacific: The Limits of Tolerance in the Twenty-First Century. The question of human rights is emerging as perhaps the most critical issue of the twenty-first century. This project aims to develop a cross-disciplinary methodology and a set of conceptual frameworks for analysing the interactions between contemporary art and global discourses on human rights in the Asia-Pacific. In the process we address the debate on universality versus cultural specificity in relation to human rights issues, and we seek to place current Australian responses to human rights in the context of the dynamically changing region in which we live.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100201
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national dig ....Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national digital humanities infrastructure by collaboratively working toward efficient discovery of data and interoperative infrastructure. Moreover the DAAO has potential as an enabling technology for Australia's Indigenous visual arts and craft sector in meeting the challenges of unethical conduct, sustainability and further developing international markets.Read moreRead less
Efficacy profiling innovation in novel pain therapeutics discovery. The purpose of this project is to bring innovation into the methods used for selecting novel compounds with high potential for progression into development as highly effective pain-killers for improving the relief of chronic pain. This will result in new pain-killers that are highly effective without producing unpleasant side-effects.
Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Empowering Australia’s Visual Arts via Creative Blockchain Opportunities. This project investigates the provision of a blockchain-based solution for protecting the intellectual property and provenance of visual art, and ways to empower its economic, cultural, and social value and benefits. By exploring innovative non-fungible token (NFT) opportunities in a global cyber security context, we will co-design a user-friendly and compliant tool for expanding the creation and movement of art on existin ....Empowering Australia’s Visual Arts via Creative Blockchain Opportunities. This project investigates the provision of a blockchain-based solution for protecting the intellectual property and provenance of visual art, and ways to empower its economic, cultural, and social value and benefits. By exploring innovative non-fungible token (NFT) opportunities in a global cyber security context, we will co-design a user-friendly and compliant tool for expanding the creation and movement of art on existing virtual galleries and smart contract-enabled platforms. Building on interdisciplinary synergies between creative and IT practices, we will interrogate the efficacy, risks and governance surrounding this global technology, and produce vital new knowledge for engaging with risks and opportunities in the digital economy.Read moreRead less
Privacy-preserving data processing on the cloud. This project aims to address the current lack of privacy of user data processed by common cloud computing web servers, including email, business data, and confidential files. This project aims to develop new techniques in cryptography. The anticipated outcome is a suite of practical tools enabling common cloud computing processing operations such as search, statistical analysis, and multi-user access control, to be performed efficiently while pres ....Privacy-preserving data processing on the cloud. This project aims to address the current lack of privacy of user data processed by common cloud computing web servers, including email, business data, and confidential files. This project aims to develop new techniques in cryptography. The anticipated outcome is a suite of practical tools enabling common cloud computing processing operations such as search, statistical analysis, and multi-user access control, to be performed efficiently while preserving the data privacy. These tools should provide significant benefits to the privacy of cloud users, as well as financial and reputation benefits to the IT industry, by significantly reducing the likelihood of massive user data privacy breaches in the event of a cyber-hacking attack on the cloud server.Read moreRead less
Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or t ....Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or the acute exacerbation of existing disease. The impact of these new technologies on the early diagnosis and improved triaging of patients in emergency departments is potentially profound and could result in improved healthcare outcomes for the patients and reduced admissions to hospital as well as the development of a substantial international market.Read moreRead less