One of the main trends in the evolution of the primate brain was the huge expansion of the cortical areas devoted to visual processing. However, the exact role of individual areas remains highly controversial, making detailed physiological and anatomical studies in suitable primate models a key step to elucidating their function in the human brain. In this project, we will address the organization of a poorly known group of visual areas, which is located deep in a part of the brain called the in ....One of the main trends in the evolution of the primate brain was the huge expansion of the cortical areas devoted to visual processing. However, the exact role of individual areas remains highly controversial, making detailed physiological and anatomical studies in suitable primate models a key step to elucidating their function in the human brain. In this project, we will address the organization of a poorly known group of visual areas, which is located deep in a part of the brain called the interhemispheric fissure (the medial complex of visual areas). Preliminary evidence suggests that these areas may provide anatomical shortcuts linking vision, behavioural reactions, and emotion. Suppose, for example, that you are sitting outside reading. Although deep in concentration, you are still able to detect the sudden movement of an approaching object in your peripheral field of vision. In many cases you can react (e.g., by ducking , or raising your arms to protect the face) long before you register what the object actually is. An adrenaline rush often accompanies these quick motor reactions, implying a parallel activation of the autonomic nervous system. While the mechanism by which the brain promotes these quick reactions remains poorly understood, we believe that the medial complex of visual areas holds the key. The aim of this study is to map the anatomical framework underlying our ability to react to sudden stimuli in our peripheral visual field. Such work is fundamental for understanding the functional organization of the brain. It also has the potential to lay the groundwork for developments in areas of applied research, including medicine (e.g. the design of better rehabilitation strategies for people with brain damage) and the cognitive sciences (e.g. a better understanding of the factors that limit human responses to visual stimuli).Read moreRead less
The GABAergic System In Eye Growth Control And Myopia
Funder
National Health and Medical Research Council
Funding Amount
$318,142.00
Summary
Shortsightedness (myopia) is the most common visual disorder. High myopia is associated with an increased risk of eye diseases. Current treatments do not stop myopia developing or decrease the associated risk of eye disease. The continued worsening of myopia is very concerning. A safe effective treatment that can either prevent myopia or stop its progression to extreme levels is needed. We have data showing that GABA ergic drugs modify myopia. This proposal will determine the mechanisms.
Multidimensional Coding Of Visual Information In The Retina
Funder
National Health and Medical Research Council
Funding Amount
$359,431.00
Summary
Although both the retina and visual cortex are part of the central nervous system, the coding of visual information in the two laminar structures differs markedly in that all three dimensions of the cortical sheet are used to code multiple response axes but only one dimension of the retinal sheet. This project examines how visual response properties are mapped through the depth of the retina and this will provide a comparatively simple paradigm of complex information processing in the brain.