Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775489
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Dictionary of Australian Artists Online, DAAO: public release version. The DAAO is already positioned as the sole system for the creation and discovery of research into art history in Australia. The DAAO will provide global exposure of Australian research and artists with tangible benefits both economically for cultural industries (including the art industry and tourism) and socially. It will also increase the breadth and depth of general knowledge of Australian art, contributing to the developm ....Dictionary of Australian Artists Online, DAAO: public release version. The DAAO is already positioned as the sole system for the creation and discovery of research into art history in Australia. The DAAO will provide global exposure of Australian research and artists with tangible benefits both economically for cultural industries (including the art industry and tourism) and socially. It will also increase the breadth and depth of general knowledge of Australian art, contributing to the development of national identity through the diversity and richness of Australia's visual cultures. Read moreRead less
Still in my mind: Gurindji experience, location and visuality. This project will develop an innovative historical account of the effects of pictorial representation of Aboriginal identity, using visual, ethnographic and archival sources. It will investigate and critique the impact of ethno-centric codification through which Aboriginal peoples have been framed and refracted throughout the 19th century and into the 21st century, from a specific Gurindji standpoint.
Creative Economy:Investigating South Australia's Creative Industries. This project aims at providing a rich and informative data set and analyses of South Australia's Creative Industries to enable a better understanding of the value networks operating in, across and beyond sectors and enable the State's creative industries to be benchmarked against their national and global counterparts. It will carry out a comprehensive, finely granulated, bottom up data gathering exercise and associated analy ....Creative Economy:Investigating South Australia's Creative Industries. This project aims at providing a rich and informative data set and analyses of South Australia's Creative Industries to enable a better understanding of the value networks operating in, across and beyond sectors and enable the State's creative industries to be benchmarked against their national and global counterparts. It will carry out a comprehensive, finely granulated, bottom up data gathering exercise and associated analyses needed at the State level to identify gaps in existing information for addressing policy settings and development. This will extend to a cross-sectoral cluster analysis and support a sustainable industry policy within the changing media environment.Read moreRead less
The Role Of Adipokines In Modulation Of Gastric Vagal Afferent Satiety Signals
Funder
National Health and Medical Research Council
Funding Amount
$624,535.00
Summary
When we feel full after a meal it is the result of a variety of different nerve signals from the gut in response to distension of the stomach and specific nutrients. These signals are disordered in obesity and may be influenced by factors released from fat stores in the body. The aim of this project is to determine how these factors interact with gastric nerve satiety signals and thus identify targets for the pharmacological treatment of obesity.
Residents’ voices: advantage, disadvantage, community and place. Community renewal and redevelopment of concentrated public housing areas represents a significant public investment aimed at improving the life chances of residents, yet the way in which place factors influence social outcomes is not well understood. This research will enhance the potential for successful outcomes by creating opportunities for residents to develop and express their own knowledge and understanding of the links betwe ....Residents’ voices: advantage, disadvantage, community and place. Community renewal and redevelopment of concentrated public housing areas represents a significant public investment aimed at improving the life chances of residents, yet the way in which place factors influence social outcomes is not well understood. This research will enhance the potential for successful outcomes by creating opportunities for residents to develop and express their own knowledge and understanding of the links between place and disadvantage, in an international context. The emergence of a theorised, contextualised and well articulated set of explanations about poverty and place from the tenant perspective will also improve public understanding and reduce the social division and stigma currently associated with public housing.Read moreRead less
Ecology, morphology and the diversification of Australian lizards. This project aims to determine the factors driving the spectacular radiation of lizards in Australia. To date, most investigations of lizard anatomy have focused exclusively on external characteristics. This project will examine the underlying internal anatomy to investigate whether morphological innovation is associated with enhanced rates of ecological, life-history and species diversification. The project expects to shed light ....Ecology, morphology and the diversification of Australian lizards. This project aims to determine the factors driving the spectacular radiation of lizards in Australia. To date, most investigations of lizard anatomy have focused exclusively on external characteristics. This project will examine the underlying internal anatomy to investigate whether morphological innovation is associated with enhanced rates of ecological, life-history and species diversification. The project expects to shed light on the evolution of Australia’s most diverse vertebrate lineage, and provide comparative data with which to interpret the lizard fossil record in Australia, and the range declines and relative extinction risks of native lizard species.Read moreRead less
Identification Of Genes For X-linked Mental Retardation.
Funder
National Health and Medical Research Council
Funding Amount
$675,228.00
Summary
We propose to identify novel heritable causes of intellectual disability using 22 large and well-characterised families from Australia. In these families we have refined the location of the genetic defect to the chromosome X and excluded the contribution of all so far known genes. We will achieve this using the technology of massive parallel sequencing. At the completion of the project we will have identified novel causes of intellectual disability and devised tests to identify them.
The Aboriginal Cardiovascular Omega-3 Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,090,119.00
Summary
CVD is the primary contributor to life expectancy differentials between Indigenous and non-Indigenous Australians. Even when cardioprotective therapies are optimally used, residual risk of adverse events is often observed. Testing of additional therapies that improve survival among Indigenous people with CVD is required. Omega 3 fatty acids can improve multiple atherogenic pathways. This trial will assess the impact of Omega 3 in Aboriginal patients with CVD.
The Role Of UPF3B And Nonsense Mediated MRNA Decay Surveillance In The Pathology Of Intellectual Disability.
Funder
National Health and Medical Research Council
Funding Amount
$789,954.00
Summary
Proper functioning of the nonsense mediated mRNA decay (NMD or 'mRNA police') is crucial for any cell to ensure normal development and function. When NMD is compromised the outcome is learning and memory problems, autism or schizophrenia. Under this project we study malfunctioning NMD using stem and neuronal cells derived from patients' skin cells. Some of the affected genes might be considered for therapeutic interventions. NMD is relevant to 1000s of human disorders and as such it is of fundam ....Proper functioning of the nonsense mediated mRNA decay (NMD or 'mRNA police') is crucial for any cell to ensure normal development and function. When NMD is compromised the outcome is learning and memory problems, autism or schizophrenia. Under this project we study malfunctioning NMD using stem and neuronal cells derived from patients' skin cells. Some of the affected genes might be considered for therapeutic interventions. NMD is relevant to 1000s of human disorders and as such it is of fundamental importance.Read moreRead less
Male-female Sperm Signalling - A Novel Pathway For Peri-conceptual Health?
Funder
National Health and Medical Research Council
Funding Amount
$674,920.00
Summary
This project will investigate a new biological process in reproduction, whereby sperm delivered to the cervix at coitus transmit signalling molecules called microRNAs that influence the female immune response, to increase the chances of conception and pregnancy. We will define the molecular details of this signalling pathway in mouse models, and then determine whether human sperm have a comparable function in ‘priming’ the female body to conceive.