Envisaging Citizenship: Australian Histories and Global Connections. This project aims to investigate the ways that visual images have defined, contested and advanced ideas of Australian citizenship and rights from European settlement to the present. Responding to the lack of a shared mainstream understanding of Australian citizenship, it looks beyond legal definitions to explore cultural and especially visual views of citizenship over time. Through collaboration with museum, media and education ....Envisaging Citizenship: Australian Histories and Global Connections. This project aims to investigate the ways that visual images have defined, contested and advanced ideas of Australian citizenship and rights from European settlement to the present. Responding to the lack of a shared mainstream understanding of Australian citizenship, it looks beyond legal definitions to explore cultural and especially visual views of citizenship over time. Through collaboration with museum, media and education sectors, it will provide a forward-looking and accessible public history, and utilise the potential of images to broaden contemporary debates about citizenship. Expected outcomes include a better public understanding of the pathways to citizenship, and enhanced engagement with Australian values and identity.Read moreRead less
Do Exposures Before Conception Influence The Risk Of Asthma In Offspring?
Funder
National Health and Medical Research Council
Funding Amount
$688,586.00
Summary
Asthma and poor lung function are major causes of public health issues. Emerging evidence suggests adverse exposures even before the conception of a child may cause these conditions. The proposed project is part of an international study across generations to identify these factors. This study will provide novel evidence to guide interventions and identify studies to advance this area further. These original findings will be of great importance both nationally and internationally.
DYRK1A As A Novel Target For Glioblastoma Therapies
Funder
National Health and Medical Research Council
Funding Amount
$620,294.00
Summary
Glioblastoma is a form of brain cancer that is currently incurable. We have discovered that switching-off an enzyme called DYRK1A (using ‘DYRK1A inhibitors’) kills glioblastoma cells. This therapeutic advantage is even greater when combined with drugs approved for other cancers. This project will develop new DYRK1A inhibitors and examine a novel combination treatment for glioblastoma patients. This could initiate a novel therapy that could significantly extend patients’ lives.
Representation of gender and sexual diversity in Australian film and television. This project aims to investigate the cultural, health and identity impact of gender/sexually-diverse characters, themes and narratives in Australian film and television from 1990 to present. The project expects to generate new knowledge by providing the first comprehensive account of Australian media production’s contribution to sexual minority representation, in the context of its importance for fostering healthy i ....Representation of gender and sexual diversity in Australian film and television. This project aims to investigate the cultural, health and identity impact of gender/sexually-diverse characters, themes and narratives in Australian film and television from 1990 to present. The project expects to generate new knowledge by providing the first comprehensive account of Australian media production’s contribution to sexual minority representation, in the context of its importance for fostering healthy identities, and acceptance of minorities to mainstream audiences in a digital media era. This knowledge will provide significant benefit to the mental health, wellbeing and social harmony for both minority and mainstream Australians and help showcase an important aspect of Australian media inclusivity and diversity in international scholarship.Read moreRead less
Ethics and aesthetics as criteria for innovation: A design research study of biological art and digital architecture. The project will contribute to the goal of promoting innovation in three areas. First, the project will amplify Australia's individual strengths in biological art and digital architecture by creating a network of artists and designers in which each discipline is stimulated by the concerns and practices of the other. Second, the project will explain innovation in such networks, by ....Ethics and aesthetics as criteria for innovation: A design research study of biological art and digital architecture. The project will contribute to the goal of promoting innovation in three areas. First, the project will amplify Australia's individual strengths in biological art and digital architecture by creating a network of artists and designers in which each discipline is stimulated by the concerns and practices of the other. Second, the project will explain innovation in such networks, by identifying activities that lead to innovation. Such an explanation will improve the nation's capacity to promote innovation in targeted fields. Third, the project will test and develop collaboration tools designed to support the activities identified as leading to innovation, as information technology is a primary enabler for operating across such networks.
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Utilitarian Filmmaking in Australia 1945 - 1980. The project plans to discover, document, analyse and compile a lasting archive of utilitarian filmmaking in Australia. 'Utilitarian' describes client-sponsored, instructional and governmental filmmaking existing outside the conventional theatrical contexts by which cinema is usually defined. Focused on the post-World War Two decades before the proliferation of video in the late 1970s, the project aims to highlight previously-unstudied aspects of t ....Utilitarian Filmmaking in Australia 1945 - 1980. The project plans to discover, document, analyse and compile a lasting archive of utilitarian filmmaking in Australia. 'Utilitarian' describes client-sponsored, instructional and governmental filmmaking existing outside the conventional theatrical contexts by which cinema is usually defined. Focused on the post-World War Two decades before the proliferation of video in the late 1970s, the project aims to highlight previously-unstudied aspects of the media industries. This is designed to deliver new knowledge of the skills and subject matter that sustained filmmaking, communication and education in Australia during a time when conventional scholarship assumes there was almost no significant filmmaking.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100056
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
Design and Art Australia Online: Sustainable data sharing for Australian researchers and collections. This project will produce a comprehensive and authorative research facility of national and international signi?cance. The enhanced Design and Art Australia Online facility will provide crucial information pertaining to Australia’s art and design heritage that will be open for researchers of all levels, from school students through to higher-education researchers.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100201
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national dig ....Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national digital humanities infrastructure by collaboratively working toward efficient discovery of data and interoperative infrastructure. Moreover the DAAO has potential as an enabling technology for Australia's Indigenous visual arts and craft sector in meeting the challenges of unethical conduct, sustainability and further developing international markets.Read moreRead less
Functional links between estuaries and their catchments: How does land use change affect estuarine ecological and bio-geochemical function? Estuaries are iconic recreational areas of high ecological and socio-economic value. Estuarine health is strongly linked to the catchments that feed them, yet we have no detailed understanding of these links. This project will use a number of state of the art approaches to better understand how land use affects estuarine health.
Antigen Selection In The MHC-restricted Cellular Immune Response
Funder
National Health and Medical Research Council
Funding Amount
$175,570.00
Summary
The body's white cells eliminate microorganisms through the actions of immune lymphocytes and other cells which conspire to kill and neutralise these unwanted guests. When microorganisms hide inside the cells of the body they are still detected by a set of T lymphocytes which have specific receptors for scrutinising the surface of cells for any changes which might signal an intracellular infection. The immune system is ever vigilant in its search for signs of infection which are generally appare ....The body's white cells eliminate microorganisms through the actions of immune lymphocytes and other cells which conspire to kill and neutralise these unwanted guests. When microorganisms hide inside the cells of the body they are still detected by a set of T lymphocytes which have specific receptors for scrutinising the surface of cells for any changes which might signal an intracellular infection. The immune system is ever vigilant in its search for signs of infection which are generally apparent when molecules called antigens are released by microorganisms and captured by the body's cells. This activates lymphocytes resulting in an immune response capable of eliminating the microorganisms. Scrutiny of the body's cells by lymphocytes occurs continuously even when there is no infection present in the body. Following infection of a cell, microbial antigens reveal the infection by their appearance on the cell surface where they are detected by the immune system's lymphocytes. This occurs through a mechanism called antigen presentation. During antigen presentation the proteins inside the cell, including those of any invading microorganism, are first degraded into shorter molecules called peptides. This event is called antigen processing. A fraction of the peptides created by antigen processing are captured by specialised receptors present on all cells. These receptors are called HLA or histocompatibility molecules. This project examines the molecular events which mediate the capture of peptide antigens by HLA molecules. The main focus is on those peptide antigens which elicit killer T cell responses by the immune system. A knowledge of how these peptides are selected for presentation and how they are captured and carried to the cell surface is fundamental to understanding immune responses to microorganisms, tumours, allergens, transplants and self tissues as in autoimmunity. Therefore the study is of great general relevance.Read moreRead less