THE UNWRITTEN HISTORY OF AUSTRALIAN MODERNISM. Most histories treat modernism in Australia as a phenomenon of ?fine art,? or simply painting. This project will instead reveal modernism's highly public impact across a range of media (design, photography, advertising, architecture and art). This new history will better explain how modernist visual idioms became ubiquitous in everyday contemporary design and our built environment after their initial, often hostile reception. The project will provid ....THE UNWRITTEN HISTORY OF AUSTRALIAN MODERNISM. Most histories treat modernism in Australia as a phenomenon of ?fine art,? or simply painting. This project will instead reveal modernism's highly public impact across a range of media (design, photography, advertising, architecture and art). This new history will better explain how modernist visual idioms became ubiquitous in everyday contemporary design and our built environment after their initial, often hostile reception. The project will provide an integrated research analysis of the extensive, but disparate, archives on Australian modernism. It will communicate its research findings through a new scholarly study, a major large-scale travelling public exhibition, a CD, and a website.Read moreRead less
Signaling Pathways To Enhance Potency Of AMPK-targeting Drugs
Funder
National Health and Medical Research Council
Funding Amount
$661,966.00
Summary
Sedentary lifestyles and consumption of high energy foods has led to epidemics of obesity-related metabolic diseases that place enormous financial and medical burden on the Australian economy. An attractive drug target to treat these diseases is AMP-activated protein kinase (AMPK) which functions as both a cellular fuel gauge and co-ordinator of whole-body metabolism. Our goal is to improve AMPK drug potency by identifying novel processes that sensitize AMPK to drugs.
A Structural Understanding Of Class B G Protein-coupled Receptor Function
Funder
National Health and Medical Research Council
Funding Amount
$1,289,570.00
Summary
G protein-coupled receptors (GPCRs) are the largest family of cell surface proteins that enable communication from external signals to the inside of cells of the body. Class B GPCRs are a therapeutically important subclass of these receptors and they play crucial roles in bone and energy homeostasis, cardiovascular control and immune response. This grant will uncover fundamental knowledge on how these receptors work, and will enhance future development of therapeutics.
Researching, designing and evaluating online learning tools to effectively utilise audio-visual archives: critical literacies through rich task interactivity. In collaboration with Film Australia and award winning eLearning company Crank Media, researchers will prototype next-generation broadband learning tools that continually assess and respond to an individual user's knowledge gaps, and enable access to digital resources derived from personal learning styles and preferences. Underpinned by di ....Researching, designing and evaluating online learning tools to effectively utilise audio-visual archives: critical literacies through rich task interactivity. In collaboration with Film Australia and award winning eLearning company Crank Media, researchers will prototype next-generation broadband learning tools that continually assess and respond to an individual user's knowledge gaps, and enable access to digital resources derived from personal learning styles and preferences. Underpinned by distributed learning theory and working with ?rich task? activities within a content aggregation scaffolding the research will design and field test innovative online study and revision activities. It will engage learners in recognizing and switching their learning paradigms appropriately, and in articulating these decisions through dynamic content pathways utilizing Film Australia's invaluable archives.Read moreRead less
Investigating, prototyping and trialling interactive online youth counselling tools. This project prototypes and trials interactive online counselling tools and evaluates their effectiveness in partnership with Australia's largest youth counselling service, Kids Help Line. There is a demonstrable need for Internet counselling practice and theory to incorporate opportunities offered by new information and communication technologies, especially to engage with the multimedia literacies of young peo ....Investigating, prototyping and trialling interactive online youth counselling tools. This project prototypes and trials interactive online counselling tools and evaluates their effectiveness in partnership with Australia's largest youth counselling service, Kids Help Line. There is a demonstrable need for Internet counselling practice and theory to incorporate opportunities offered by new information and communication technologies, especially to engage with the multimedia literacies of young people. The project will investigate multi-user graphical interactivity in youth counselling and develop an evidence base for advances in online counselling worldwide. It will research and prototype graphical tools based on traditional counselling methods to improve service delivery, and benefit the wellbeing of young Australians.Read moreRead less
Discovery And Development Of Better Pain Treatments
Funder
National Health and Medical Research Council
Funding Amount
$9,613,850.00
Summary
Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clini ....Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.Read moreRead less
Testing metabolic theories in ecology. There are striking similarities in the way plants and animals take up and use energy (metabolism), despite enormous variation in size and life-style. This project will make the first experimental comparison of the predictions of the two major theories for these broad patterns. The results will significantly progress this controversial and exciting field.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100201
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national dig ....Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national digital humanities infrastructure by collaboratively working toward efficient discovery of data and interoperative infrastructure. Moreover the DAAO has potential as an enabling technology for Australia's Indigenous visual arts and craft sector in meeting the challenges of unethical conduct, sustainability and further developing international markets.Read moreRead less
Functional links between estuaries and their catchments: How does land use change affect estuarine ecological and bio-geochemical function? Estuaries are iconic recreational areas of high ecological and socio-economic value. Estuarine health is strongly linked to the catchments that feed them, yet we have no detailed understanding of these links. This project will use a number of state of the art approaches to better understand how land use affects estuarine health.
Assessing the ecosystem-wide risks of threatened species translocation. Assessing the ecosystem-wide risks of threatened species translocation. This project aims to develop the first quantitative risk assessment framework to improve decisions about moving threatened species to new places. Moving threatened plants and animals to new environments, or reintroducing them where they previously persisted, is a growing focus of conservation. Moving species can have unanticipated effects on other specie ....Assessing the ecosystem-wide risks of threatened species translocation. Assessing the ecosystem-wide risks of threatened species translocation. This project aims to develop the first quantitative risk assessment framework to improve decisions about moving threatened species to new places. Moving threatened plants and animals to new environments, or reintroducing them where they previously persisted, is a growing focus of conservation. Moving species can have unanticipated effects on other species in the ecosystem. Although the International Union for Conservation of Nature deems ecosystem-wide risk assessments essential for conservation translocations, no framework exists to assess these risks and inform these decisions. New tools for assessing the risks of conservation translocations are expected to improve global and local conservation outcomes.Read moreRead less