Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Art and Human Rights in the Asia-Pacific: The Limits of Tolerance in the Twenty-First Century. The question of human rights is emerging as perhaps the most critical issue of the twenty-first century. This project aims to develop a cross-disciplinary methodology and a set of conceptual frameworks for analysing the interactions between contemporary art and global discourses on human rights in the Asia-Pacific. In the process we address the debate on universality versus cultural specificity in rel ....Art and Human Rights in the Asia-Pacific: The Limits of Tolerance in the Twenty-First Century. The question of human rights is emerging as perhaps the most critical issue of the twenty-first century. This project aims to develop a cross-disciplinary methodology and a set of conceptual frameworks for analysing the interactions between contemporary art and global discourses on human rights in the Asia-Pacific. In the process we address the debate on universality versus cultural specificity in relation to human rights issues, and we seek to place current Australian responses to human rights in the context of the dynamically changing region in which we live.Read moreRead less
Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air insi ....Unsaturation of vapour pressure inside leaves: fundamental, but unknown. This project aims to determine when and to what extent the air inside leaves becomes unsaturated with water vapour. All current interpretation and modelling of leaf gas exchange assumes saturation under all circumstances. Compelling evidence has been obtained that suggests this is not true under moderate air vapour pressure deficits. A novel technique will be employed to assess the water vapour concentration of the air inside leaves based on stable isotope analysis of carbon dioxide and water vapour exchanged between leaves and air. The project is expected to provide fundamental knowledge about how stomata regulate photosynthesis and water use, with significant implications for modelling vegetation function and for improving the performance of crop plants.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100201
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national dig ....Design and art of Australia online, a transformation of the dictionary of Australian artists online. The Design & Art of Australia Online (DAAO) archive provides global exposure for Australian scholarship on art and design, along with tangible economic, social and cultural benefits toward the sustainability of cultural industries.
The next generation of the DAAO will enable cultural policy to be informed by an expanded and growing collection of scholarly research. It contributes to national digital humanities infrastructure by collaboratively working toward efficient discovery of data and interoperative infrastructure. Moreover the DAAO has potential as an enabling technology for Australia's Indigenous visual arts and craft sector in meeting the challenges of unethical conduct, sustainability and further developing international markets.Read moreRead less
Will stomatal responses to humidity and carbon dioxide constrain tropical forest productivity as atmospheric carbon dioxide rises? This project will investigate two physiological processes that will partly determine growth responses of tropical forest trees to rising atmospheric carbon dioxide. The project will produce equations summarising physiological responses that can be incorporated into process-based models of tropical forest productivity.
Reading the isotopic archive: carbon and oxygen stable isotope ratios as recorders of plant physiological processes. This project will investigate how plant physiological processes are reflected in stable isotope ratios of carbon and oxygen in plant tissues. Results will contribute towards a mechanistic understanding of the processes that cause isotopic modifications, thereby enabling an improved interpretation of naturally occurring stable isotope signals.
Functional links between estuaries and their catchments: How does land use change affect estuarine ecological and bio-geochemical function? Estuaries are iconic recreational areas of high ecological and socio-economic value. Estuarine health is strongly linked to the catchments that feed them, yet we have no detailed understanding of these links. This project will use a number of state of the art approaches to better understand how land use affects estuarine health.
Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spri ....Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spring-like function of the foot. It will explain a conceptually novel design allowing shoes to support our feet, whilst harnessing the energetic benefits of the foot's spring-like function. This research has the potential to revolutionise athletic footwear design and has direct implications for enhanced performance in running athletes.Read moreRead less
Linking phytoplankton to fisheries using zooplankton size spectra. This project aims to develop innovative numerical methods to understand the dynamics, carbon export, and trophic structure of zooplankton. The trophic links between phytoplankton, zooplankton and fisheries are unknown. The size- frequency distribution of zooplankton (size spectrum) is an innovative method for estimating their growth, predation and production as food for fish. Analysis of a global synthesis of zooplankton size dis ....Linking phytoplankton to fisheries using zooplankton size spectra. This project aims to develop innovative numerical methods to understand the dynamics, carbon export, and trophic structure of zooplankton. The trophic links between phytoplankton, zooplankton and fisheries are unknown. The size- frequency distribution of zooplankton (size spectrum) is an innovative method for estimating their growth, predation and production as food for fish. Analysis of a global synthesis of zooplankton size distributions from tropical to polar environments are expected to reveal these vital rates of pelagic ecosystems. The zooplankton rates will reveal, for the first time, the link between phytoplankton and fisheries, and will significantly improve ecosystem models and global assessments of environmental change.Read moreRead less
Empowering Australia’s Visual Arts via Creative Blockchain Opportunities. This project investigates the provision of a blockchain-based solution for protecting the intellectual property and provenance of visual art, and ways to empower its economic, cultural, and social value and benefits. By exploring innovative non-fungible token (NFT) opportunities in a global cyber security context, we will co-design a user-friendly and compliant tool for expanding the creation and movement of art on existin ....Empowering Australia’s Visual Arts via Creative Blockchain Opportunities. This project investigates the provision of a blockchain-based solution for protecting the intellectual property and provenance of visual art, and ways to empower its economic, cultural, and social value and benefits. By exploring innovative non-fungible token (NFT) opportunities in a global cyber security context, we will co-design a user-friendly and compliant tool for expanding the creation and movement of art on existing virtual galleries and smart contract-enabled platforms. Building on interdisciplinary synergies between creative and IT practices, we will interrogate the efficacy, risks and governance surrounding this global technology, and produce vital new knowledge for engaging with risks and opportunities in the digital economy.Read moreRead less