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Pathways To Vision Following Lesions Of The Primary Visual Cortex
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Lesions due to stroke or trauma in the occipital lobe cause blindness, which can be complete or restricted to part of the visual field. My work has identified areas of the visual brain that remain active after such lesions. I want to find out if these areas can be used to partially restore vision. This project will study the potential roles of different surviving areas, how brain cells rewire their connections in response to damage, and how rehabilitation programs work at the cellular level.
The Pulvinar Is Instrumental In The Development Of Visual Cortical Networks
Funder
National Health and Medical Research Council
Funding Amount
$1,192,911.00
Summary
This Project will elucidate the mechanisms and brain structures involved in visual system development and how their perturbation in early life can lead to neurodevelopmental and cognitive brain disorders, such as Williams and fragile-X syndromes as well as dyslexia. Furthermore, it will demonstrate how the visual brain has a greater capacity to compensate and achieve preservation of vision following an injury in early life.
Lesions of the primary visual area (V1) are sufficient to cause blindness, even though there are many other brain areas normally involved in vision. However, when V1 is lesioned very early in life people show some recovery, and may be able to see well enough to perform everyday activities. In order to understand what happens in the brain that allows this preservation of vision, we will study changes in the pathways linking the eyes to the brain, following lesions at different ages.