Blocking Human Cytomegalovirus: Targeting Host Organelle Remodelling And The Viral Assembly Complex
Funder
National Health and Medical Research Council
Funding Amount
$553,477.00
Summary
Human cytomegalovirus (HCMV) is a human pathogen that infects over 60% of adults, is a significant cause of morbidity and mortality in immuno-compromised people, and a major cause of birth defects. Fundamental knowledge gaps remain in understanding host-pathogen relationships during infection. This project will systematically define molecular events giving rise to release of virus from an infected cell, and thereby reveal novel targets to block therapeutically.