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Cracking the code of snails to elucidate parasite disease transmission. In Australia, a disease caused by liver flukes causes major economic losses to livestock production. The role of Australian pond snails as intermediate hosts for this parasite is poorly understood. This project aims to explore the phylogeography, biology and genomics of these snails. It expects to create novel molecular resources for important snail species and verify their roles as key vectors of flatworm parasites. The cur ....Cracking the code of snails to elucidate parasite disease transmission. In Australia, a disease caused by liver flukes causes major economic losses to livestock production. The role of Australian pond snails as intermediate hosts for this parasite is poorly understood. This project aims to explore the phylogeography, biology and genomics of these snails. It expects to create novel molecular resources for important snail species and verify their roles as key vectors of flatworm parasites. The curation of genomic and transcriptomic data sets, and elucidation of snail–parasite interactions will underpin the development of environmental diagnostic tests and deliver a new generation of intervention strategies to reduce the burden of liver fluke disease through the control of their snail intermediate hosts.Read moreRead less
Negotiating caring and employment - the impact on carers' wellbeing. Work and caring compete for carers? time. Little is known about the difficulties of combining work with the care of adults or children with disabilities. Between 40 and 60 percent of Australian carers combine employment with caring responsibilities. The project proposes to adopt a life-course perspective to study the effect of caring on income security, social participation and the health of employed carers. It makes innovative ....Negotiating caring and employment - the impact on carers' wellbeing. Work and caring compete for carers? time. Little is known about the difficulties of combining work with the care of adults or children with disabilities. Between 40 and 60 percent of Australian carers combine employment with caring responsibilities. The project proposes to adopt a life-course perspective to study the effect of caring on income security, social participation and the health of employed carers. It makes innovative use of existing data sources, including new longitudinal survey data, supported by a specially designed program of qualitative research to study key transitions, possible workplace solutions and the effective provision of human services.Read moreRead less
Innovation in agricultural sector Green House Gas abatement in NSW. This project aims to develop a land sector greenhouse gas abatement, food production and environmental economics model for NSW. We expect to identify innovation in carbon payment policy and brokerage business models to achieve agricultural GHG abatement, while simultaneously improving sustainability. Expected outcomes include evaluation of the innovations of expert landholders, related businesses and governments to find ways to ....Innovation in agricultural sector Green House Gas abatement in NSW. This project aims to develop a land sector greenhouse gas abatement, food production and environmental economics model for NSW. We expect to identify innovation in carbon payment policy and brokerage business models to achieve agricultural GHG abatement, while simultaneously improving sustainability. Expected outcomes include evaluation of the innovations of expert landholders, related businesses and governments to find ways to influence land use decisions. This should provide significant benefits to landholders, governments involved in land management and the public through increased productivity, profitability, biodiversity and ecosystem health in the context of future climate, agricultural commodity and carbon market uncertainties.Read moreRead less
Quality and outcomes of individual supported living arrangements for adults with intellectual and developmental disabilities. This project identifies service quality aspects contributing to positive outcomes in individual supported living arrangements that enable adults with developmental disabilities to live in their own homes. 150 arrangements will be evaluated across Western Australia, New South Wales and Victoria, providing evidence of service quality in support of people with disability hav ....Quality and outcomes of individual supported living arrangements for adults with intellectual and developmental disabilities. This project identifies service quality aspects contributing to positive outcomes in individual supported living arrangements that enable adults with developmental disabilities to live in their own homes. 150 arrangements will be evaluated across Western Australia, New South Wales and Victoria, providing evidence of service quality in support of people with disability having choice and control in their living arrangements.Read moreRead less
Novel Early Warning System for Hypoglycaemia. An innovative technique will be developed for early detection of low blood glucose level (hypoglycaemia), a life-threatening complication affecting millions of people with Type 1 diabetes worldwide. Real-time analysis of the effectiveness of skin impedance, ECG (in particular heart rate and QT interval), and EEG (alpha wave) will be combined with robust adaptive neural networks to provide a novel theoretical and practical basis for developing a non-i ....Novel Early Warning System for Hypoglycaemia. An innovative technique will be developed for early detection of low blood glucose level (hypoglycaemia), a life-threatening complication affecting millions of people with Type 1 diabetes worldwide. Real-time analysis of the effectiveness of skin impedance, ECG (in particular heart rate and QT interval), and EEG (alpha wave) will be combined with robust adaptive neural networks to provide a novel theoretical and practical basis for developing a non-invasive hypoglycaemia monitor. This device has the potential to save lives, improve quality of life for people with diabetes and their carers, and put Australia at the forefront in this $US5 billion pa industry.Read moreRead less
Innovative hands-free technology to give the severely disabled greater mobility control. Half of the serious neurological injuries in Australia result in tetraplegia. Combined with other disabilities that involve severe mobility impairments the cost to the community economically, psychologically and socially is huge. This new Australian technology will facilitate effective sharing of control between a disabled person and a computer control system, taking advantage of their unique strengths and e ....Innovative hands-free technology to give the severely disabled greater mobility control. Half of the serious neurological injuries in Australia result in tetraplegia. Combined with other disabilities that involve severe mobility impairments the cost to the community economically, psychologically and socially is huge. This new Australian technology will facilitate effective sharing of control between a disabled person and a computer control system, taking advantage of their unique strengths and enabling each to aid the other in areas of weakness. The social and personal benefits are potentially very large. Scope also exists to significantly reduce healthcare costs and to develop a new industry in hands-free technology.Read moreRead less
Optimising Benefits And Minimising Potential Harms Of Obesity Treatments
Funder
National Health and Medical Research Council
Funding Amount
$707,370.00
Summary
This work aims to find safe and more effective obesity treatments for the over 2.1 billion people worldwide with overweight or obesity. Severely energy restricted diets are currently the most effective dietary obesity treatment, but these are underutilized due to concerns about potential harms. This work will investigate using severe diets intermittently rather than continuously, as a means of enhancing their benefits of long-term weight/fat loss while also reducing potential harmful effects.
Improving Weight Loss By Intermittent Use Of Very Low Energy Diet: The TANGO Diet Trial (Temporary Phases Of Accelerated Weight Loss For Noticeably Greater Outcomes)
Funder
National Health and Medical Research Council
Funding Amount
$660,736.00
Summary
Very low energy diet (VLED) is being increasingly used for the treatment of obesity, but the resultant weight loss is usually transient, partly because it induces powerful adaptive responses that inhibit weight loss and promote regain. We have shown that 'taking a break from dieting' for 2 weeks reduces these adaptive responses. In this project we will thus test whether weight loss outcomes with VLED can be improved via intermittent use, where periods on the VLED are alternated with 'breaks'.
Corrosion of heat resisting alloys in steam/hydrogen-rich environment . Hydrogen is a clean fuel for energy future. Its production and utilisation unavoidably involve water vapour and hydrogen at high temperature which is however corrosive to materials used in the system. This project aims to investigate corrosion behaviour of heat resistant alloys in the presence of both hydrogen and water vapour, mechanisms of water transport in oxide scale, and the effect of hydrogen on water vapour corrosion ....Corrosion of heat resisting alloys in steam/hydrogen-rich environment . Hydrogen is a clean fuel for energy future. Its production and utilisation unavoidably involve water vapour and hydrogen at high temperature which is however corrosive to materials used in the system. This project aims to investigate corrosion behaviour of heat resistant alloys in the presence of both hydrogen and water vapour, mechanisms of water transport in oxide scale, and the effect of hydrogen on water vapour corrosion. Alloying effects on corrosion rates will be defined and methods of slowing or preventing water vapour corrosion in the presence of hydrogen will be devised. The results will provide a basis for improved design/selection of heat resisting alloys for hydrogen production and hydrogen utilisation industries.Read moreRead less
Wicked defaults: how to overcome the dark side of choice architecture. This project aims to investigate how defaults and product complexity might be used to exploit consumers in environments like private insurance where consumers are prone to making systematic errors. Defaults are used to nudge individuals into socially beneficial actions such as increasing their retirement savings and joining organ donor lists. However, in the hands of firms, defaults can also be used to exploit consumers by en ....Wicked defaults: how to overcome the dark side of choice architecture. This project aims to investigate how defaults and product complexity might be used to exploit consumers in environments like private insurance where consumers are prone to making systematic errors. Defaults are used to nudge individuals into socially beneficial actions such as increasing their retirement savings and joining organ donor lists. However, in the hands of firms, defaults can also be used to exploit consumers by encouraging choices that help the firm but disadvantage consumers. The project intends to study experimentally whether exploitation can be reduced via competition and reputation building systems based on consumer feedback.Read moreRead less