Assessing Acellular Pertussis Vaccine Effectiveness: Integrating Transmission Models, Genetics And Cohort Data To Inform Policy
Funder
National Health and Medical Research Council
Funding Amount
$429,597.00
Summary
Between 2009-12 a very large epidemic of whooping cough occurred in Australia. More surprisingly during the course of the epidemic the bacteria that cause whooping cough showed genetic changes that seemed to avoid protection provided by the current vaccine against whooping cough in Australia. This grant seeks to use mathematical models of whooping cough transmission to explain how this occurred and to establish whether alternative vaccination strategies might improve the control of this disease.
Vaccination Timeliness In Aboriginal And Non-Aboriginal Infants: Risk Factors For Delayed Vaccination And Impact On Disease Burden—a Record Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$538,183.00
Summary
Vaccination has had a significant impact, but preventable infections continue to occur, perhaps due to delayed uptake of scheduled doses. For the first time, we will link vaccination and other health records to: provide accurate estimates of the impact of vaccination; identify reasons for delayed vaccination; and quantify the expected reduction in disease burden if vaccination timeliness was improved. The study will help determine who would benefit most from efforts to improve timeliness.
Combining Health, Laboratory And Immunisation Data Sources To Identify Opportunities For The Prevention Of Chest Infections In Young Aboriginal And Non-Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$428,469.00
Summary
Chest infections are one of the major reasons children are admitted to hospital, particularly in Aboriginal children. This project will determine whether current vaccines have reduced hospital visits and how many children are affected by multiple infections. It will also identify where better vaccination programs are needed. This will be done by bringing together and analysing a range of infection and hospital records to paint a true picture of the impact of chest infections in children.