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Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.
Complete the 5 min survey now by clicking on the link below.
Halting The Spread Multidrug Resistant Uropathogenic E. Coli
Funder
National Health and Medical Research Council
Funding Amount
$687,975.00
Summary
Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract infection (UTI) and increasingly associated with resistance to multiple antibiotics. This project will study the virulence of multidrug resistant UPEC and use this knowledge to develop new approaches to treat and prevent UTI. The outcomes will be applicable to one of the most common infectious diseases of humans and have broad-reaching impact on our understanding of other infections caused by Gram-negative pathogens.
Development Of New Therapies For Respiratory Diseases And Infection
Funder
National Health and Medical Research Council
Funding Amount
$847,490.00
Summary
Prof Hansbro’s group have developed world 1st experimental models of emphysema, severe asthma infection and lung cancer. He uses them to further our understanding of these untreatable diseases. This has led to the development of new potential therapeutic approaches. Now, in discovery programs he will expand studies of pathogenesis to identify new therapeutic targets these diseases. In development and translational programs he will progress new therapies towards clinical application.
Helminth Secretomes: From Vaccines To Novel Anti-inflammatory Biologics
Funder
National Health and Medical Research Council
Funding Amount
$938,910.00
Summary
Billions of people in developing countries are infected with parasitic worms, but they have been eradicated from industrialised nations. Humans co-evolved with worms, so their recent removal has deprived us of signals required to keep inflammation in check. My research focuses on worm molecules that can be used to (1) develop vaccines to combat these parasitic infections in developing countries, and (2) as a novel platform of anti-inflammatory therapeutics for use in industrialised nations.
Type 2 Immunity: A Regulator Of Physiology, Tissue Repair And Metabolism
Funder
National Health and Medical Research Council
Funding Amount
$640,210.00
Summary
Intestinal helminths (worms) have evolved together with humans and induce strong type 2 immune responses effective at eradicating the parasite, mediating tissue repair and modulating the gut microbiota. My research aims to decipher the roles of type 2 immunity in regulating intestinal health and promoting tissue repair. I also plan to determine how worm infection and type 2 immunity modulate the microbiota the impact of this on health, particularly obesity.
Protecting Australia And The Region From Emerging And Re-emerging Infectious Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$774,540.00
Summary
The world is facing unprecedented threats from epidemics. In 2014 Ebola showed that issues such as quarantine, personal protective equipment and improved health system capacity are just as critical as drugs and vaccines, yet these are under-researched. Professor MacIntyre is an international expert epidemic control. She will lead a strategic research program to improve control of emerging and re-emerging infections, using her expertise in vaccines, personal protective equipment and biosecurity.
New Interventions To End Neglected Tropical Diseases In Asia
Funder
National Health and Medical Research Council
Funding Amount
$926,980.00
Summary
My research goal is to eliminate parasitic worm infestations globally. These parasites cause substantial illness and affect the world's poorest people. Programs that drug treat infected individuals operate but these are neither effective nor sustainable. Our research has shown that additional measures, such as vaccination and health education, are needed and we aim to develop and field test a combination of interventions that will lead to their sustainable control and eventual elimination.
New Antibiotics And Treatment Methods Against Drug-resistant Bacteria
Funder
National Health and Medical Research Council
Funding Amount
$766,468.00
Summary
Infectious disease is a leading cause of death, and the emergence of "superbugs" in the community and hospitals is of grave concern. We are developing new, powerful antibiotics that can kill superbugs using ‘forgotten’ drugs from the 1970s. These will combat bacteria that cause pneumonia, skin and urinary track infections; diseases that cause death and discomfort for thousands of Australians today. We will also develop methods to directly remove bacteria from blood infections.
Defining The Coordination Of Immune Responses To Pathogens
Funder
National Health and Medical Research Council
Funding Amount
$640,210.00
Summary
Understanding how immune responses are coordinated is critical for the design of new therapies and vaccines to target infectious diseases and cancers. This project will utilise advanced imaging combined with novel tools to dissect the complex interactions that occur between immune cells as they are activated and patrol the body to eliminate infectious pathogens.
Regulation Of Nucleocytoplasmic Transport; Role In Health And Disease
Funder
National Health and Medical Research Council
Funding Amount
$823,008.00
Summary
Transport into and out of the nucleus is central to the function of the cells from complex organisms such as mammals. This research program aims to improve understanding of nuclear transport and its regulation in the context of infection by medically relevant viruses, as well as in the context of cancer, and normal cell growth/development. It will contribute to developing new anti-viral therapeutics/vaccines, drug delivery strategies for cancer, and understanding causes of male infertility.
Innovative Approaches To Reducing The Impact Of Blood Borne Viruses And Sexually Transmitted Infections On Young People.
Funder
National Health and Medical Research Council
Funding Amount
$246,859.00
Summary
Over the next 5 years I will undertake a program of research centred on reducing the impact of blood-borne viruses (BBVs) and sexually transmitted infections (STIs) in vulnerable populations, particularly young people. I will study how these infections are transmitted, associated risk behaviours including drug and alcohol use and sexual risk, and develop interventions to improve the detection and management of infected individuals.