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Scheme : Discovery Projects
Australian State/Territory : WA
Research Topic : tumour biology
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  • Researchers (9)
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  • Active Funded Activity

    Discovery Projects - Grant ID: DP240102441

    Funder
    Australian Research Council
    Funding Amount
    $520,376.00
    Summary
    Control of crop-microbe symbiosis by new plant hormones. This project aims to discover how plants use hormone-like chemicals, called butenolides, to control symbiotic relationships with soil fungi. It will use multidisciplinary and collaborative techniques to establish how butenolide metabolism affects the diversity of fungal colonisation. Expected outcomes of this project include a deeper understanding of how plants regulate the competency of roots to host symbiotic fungi, and how this affects .... Control of crop-microbe symbiosis by new plant hormones. This project aims to discover how plants use hormone-like chemicals, called butenolides, to control symbiotic relationships with soil fungi. It will use multidisciplinary and collaborative techniques to establish how butenolide metabolism affects the diversity of fungal colonisation. Expected outcomes of this project include a deeper understanding of how plants regulate the competency of roots to host symbiotic fungi, and how this affects plant growth. As such, it will generate knowledge of how cereals such as barley could be modified to improve their nutrient use efficiency. Benefits of this project include the potential to reduce fertiliser inputs, thereby improving the competitiveness and environmental impact of Australian agriculture.
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    Funded Activity

    Discovery Projects - Grant ID: DP130104205

    Funder
    Australian Research Council
    Funding Amount
    $420,000.00
    Summary
    What is the function of gamma-aminobutyric acid-gated anion channels in plants? The project will identify the molecular basis of gamma-aminobutyric acid (GABA) signalling in plants. This is significant because GABA regulates proteins that release molecules involved in root-soil interactions, growth, and fertilisation. The project's discoveries will allow improvement of these agronomic traits that ultimately determine crop yield.
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    Funded Activity

    Discovery Projects - Grant ID: DP170104384

    Funder
    Australian Research Council
    Funding Amount
    $375,000.00
    Summary
    A signalling pathway for future crop improvement. This project aims to decipher a mechanism that controls plant gas exchange – the process that emits oxygen, loses water, absorbs carbon dioxide and is essential for plant growth for food, fibre and fuel production. When plants encounter stressful conditions such as drought, high temperatures or flooding, they adapt their physiology to maintain viability and re-establish growth. This project will manipulate stress-induced gamma-aminobutyric acid’s .... A signalling pathway for future crop improvement. This project aims to decipher a mechanism that controls plant gas exchange – the process that emits oxygen, loses water, absorbs carbon dioxide and is essential for plant growth for food, fibre and fuel production. When plants encounter stressful conditions such as drought, high temperatures or flooding, they adapt their physiology to maintain viability and re-establish growth. This project will manipulate stress-induced gamma-aminobutyric acid’s capacity to control plant gas exchange to help secure future food production, through improving crop tolerance to stresses such as low water availability and high temperatures – conditions associated with a changing Australian climate.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP210102828

    Funder
    Australian Research Council
    Funding Amount
    $509,000.00
    Summary
    Investigating a novel signalling pathway for crop improvement. This project will dissect a newly identified signalling pathway in plants that regulates plant water use and carbon gain. It will deploy multiple techniques, including novel biosensors, to understand the links between the metabolism of plants and their environmental responses. The project will build partnerships with scientists at leading international institutions for enhanced outcomes, including access to specialised equipment and .... Investigating a novel signalling pathway for crop improvement. This project will dissect a newly identified signalling pathway in plants that regulates plant water use and carbon gain. It will deploy multiple techniques, including novel biosensors, to understand the links between the metabolism of plants and their environmental responses. The project will build partnerships with scientists at leading international institutions for enhanced outcomes, including access to specialised equipment and upskilling of our scientists. The generation of barley with the latest gene editing techniques aims to produce a non-GM crop with the potential for enhanced root C sequestration, lower water use and improved yield, three key goals for agricultural sustainability in the face of a drying Australian climate.
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    Funded Activity

    Discovery Projects - Grant ID: DP120102081

    Funder
    Australian Research Council
    Funding Amount
    $380,000.00
    Summary
    Scaling of structure, function and energetics of the vertebrate cardiovascular system. The hearts of mammals, reptiles and fish do different amounts of work, depending on the animal’s metabolic rate and body size. This project attempts to understand why hearts are the size and thickness that they are, and whether this results in minimising the work necessary to satisfy the requirements of the animal.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP180101688

    Funder
    Australian Research Council
    Funding Amount
    $371,347.00
    Summary
    How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex .... How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex traits.
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    Funded Activity

    Discovery Projects - Grant ID: DP110100726

    Funder
    Australian Research Council
    Funding Amount
    $285,000.00
    Summary
    Evolution in tooth and claw: exploring the relationship between the radiation of marsupial herbivores and late Cenozoic climate change. Establishing how animals responded to past environmental changes is essential for understanding the ecology of modern species and managing them in light of contemporary climatic trends. By applying several novel analytical methods this project will unravel the links between the radiation of Australian marsupials and key stages in climatic evolution.
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    Funded Activity

    Discovery Projects - Grant ID: DP120104435

    Funder
    Australian Research Council
    Funding Amount
    $380,000.00
    Summary
    Faunal responses to environmental change and isolation on an Australian land-bridge island. Establishing how faunas responded to past isolation and environmental changes offers great potential for predicting long-term impacts of habitat fragmentation. By combining novel methods we will track extinction rates, diet and body-size shifts on Kangaroo Island, the only known land-bridge island with a fossil record spanning the past 100,000 years.
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    Funded Activity

    Discovery Projects - Grant ID: DP190103636

    Funder
    Australian Research Council
    Funding Amount
    $445,000.00
    Summary
    Illuminating the evolutionary history of Australia’s most iconic animals. This project aims to pinpoint the nature and timing of key steps in macropod history and to test how these link with major climatic and biotic changes. Macropods (kangaroos and relatives) are widely considered the marsupial equivalents to hoofed mammals on other continents, but we have a weaker understanding of how their evolution was shaped by environmental change. This project will combine palaeontology, anatomy and gene .... Illuminating the evolutionary history of Australia’s most iconic animals. This project aims to pinpoint the nature and timing of key steps in macropod history and to test how these link with major climatic and biotic changes. Macropods (kangaroos and relatives) are widely considered the marsupial equivalents to hoofed mammals on other continents, but we have a weaker understanding of how their evolution was shaped by environmental change. This project will combine palaeontology, anatomy and genetics to address questions such as how and why ancestral macropods descended from the trees and evolved bipedal hopping, and the upper size limits of the kangaroo “body plan”. This should improve our understanding of the long-term effects of climate change on marsupials, and provide a test of key placental-based evolutionary models.
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    Showing 1-9 of 9 Funded Activites

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