Development of dense gas technology platforms for the formulation of oral vaccines. This project will aim to develop a technology platform that enables the formulation of vaccines that can be delivered orally and this research has the potential to radically change existing vaccination regimens. The availability of needle-free vaccination also has potential for considerable societal and economic impact in developing countries.
A new approach to reversing and preventing immune-mediated diseases. Chronic inflammatory diseases affect up to 20 per cent of Australians. These diseases reduce wellbeing and life potential and shorten lifespan. This project addresses the urgent need for effective therapies and focuses on developing strategies for disease cure and prevention.
Protecting young people from harm and injury: investigating the utility of a risk and protective framework. Serious injuries due to transport, violence and alcohol associated risk-taking are the main cause of teenage death. An innovative school course will be taught and evaluated that increases protecting others from risk, helping injured friends and promoting a connected environment where teachers and peers reach out to provide support.
Patients' preference for participation in patient safety activities. This study will identify patient and nurse perceptions of involving patients in patient safety activities. Priorities for implementing strategies to support patient participation in patient safety activities will be identified, which will influence both health policy and practice.
Mathematical modelling can provide vital information on the effectiveness and practical implementation of microbicides and vaccines against HIV. This project will produce mathematical models of the earliest stages of HIV infection suitable for investigation of the implementation of vaccines and microbicides. It will provide a framework to investigate why these interventions have performed poorly to date, and how these may be better implemented.
Genomic strategies for reducing losses during processing and improving the nutritional value of wheat in human diets. Wheat breeding requires efficient tools to allow selection of varieties with both high grain yield and good functional and nutritional value. Whole genome analysis will be used to develop screening methods to deliver wheat varieties with novel processing and nutritional properties for human diets contributing to global food and nutritional security.
Molecular and immunological approaches to managing Australia's seafood allergy epidemic. Seafood is an increasingly important cause of food allergy. Novel insight into the functions of why and how proteins from seafood develop to potent allergens will lead to the development of better diagnostics and therapeutics. This will assist patients to better manage their serious food allergy.
Psychological strategies for maximum health and enjoyment during moderate intensity and vigorous physical exercise. This project will change the way people think during physical exercise. It will show adults of all ages and levels of experience how to get more out of moderate intensity and vigorous exercise by reducing perceived effort and making it more enjoyable.
Skin penetration of nanoparticles promoted by particle design, formulation and application method. This project seeks to better define the determinants of nanoparticle skin penetration and subsequent disposition in the body. The data would be used to guide minimal skin penetration of 'undesirable' nanoparticles and the properties required of 'safe' nanoparticles to enable effective human skin delivery in cosmetic and dermatological products.
Understanding how local and regional accessibility are associated with active travel, and related health and economic impacts. Exercise and walking are vital for a healthy lifestyle and wellbeing. The accessibility and ’walkability’ of where one lives and works is key to supporting physical activity. Consequently, public health practitioners, urban planners and the transport sector face a common strategic challenge; shifting people from private vehicles to active forms of transport. This project ....Understanding how local and regional accessibility are associated with active travel, and related health and economic impacts. Exercise and walking are vital for a healthy lifestyle and wellbeing. The accessibility and ’walkability’ of where one lives and works is key to supporting physical activity. Consequently, public health practitioners, urban planners and the transport sector face a common strategic challenge; shifting people from private vehicles to active forms of transport. This project aims to model the health and economic impacts of the ease of: walking and cycling within neighbourhoods; and travelling across wider geographical areas on time spent walking and cycling for transport among both adults and children. This project aims to enable the research team to maximise the opportunities the environment provides for both positive health and well-being in Australia.Read moreRead less