Helping Stroke Physicians Choose Who To Thrombolyse - The Targeting Optimal Thrombolysis Outcomes (TOTO) Study
Funder
National Health and Medical Research Council
Funding Amount
$1,073,140.00
Summary
Thrombolysis using alteplase is one of the most effective treatments for stroke but is currently used in only 5% of stroke cases. A major barrier is a lack of tools to identify who will benefit from treatment, or who might have a major adverse event. In this study we will develop a clinical decision rule based on clinical data, advanced CT imaging, and blood biomarkers to help identify those who will benefit and those likely to bleed, to encourage wider use of this treatment in acute stroke.
Stroke In Australia: Understanding Variation In Clinical Care And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Stroke is the major cause of death and disability. My ECF research project is designed to identify (1) factors that influence hospital readmissions (2) gaps in hospital care for specific groups who experience stroke using the largest national dataset (40+ hospitals, 17,000+ patients). These data will provide evidence for me to develop and test novel future interventions to reduce inequalities in health care access in order to reduce deaths and disability through improvements in stroke care.
The Effects Of Treating Comorbid Social Phobia In Adults Who Stutter
Funder
National Health and Medical Research Council
Funding Amount
$196,245.00
Summary
Stuttering is a distressing and common speech disorder that prevents normal communication, hinders attainment of occupational potential, and can cause a lifetime of embarrassment and anxiety in everyday speaking situations. Around half of all adults who stutter have a condition called social phobia, which involves excessive anxiety in social situations. This is an important observation, because it is well known that treatments for adults who stutter are not particularly effective for some patien ....Stuttering is a distressing and common speech disorder that prevents normal communication, hinders attainment of occupational potential, and can cause a lifetime of embarrassment and anxiety in everyday speaking situations. Around half of all adults who stutter have a condition called social phobia, which involves excessive anxiety in social situations. This is an important observation, because it is well known that treatments for adults who stutter are not particularly effective for some patients. In this research project, we investigate the possibility that this is because existing treatments have not addressed the fact that many adults who stutter have levels of social anxiety in everyday speaking situations. In this experiment, half the subjects receive a standard treatment and the other half receive a standard treatment plus cognitive behaviour therapy designed to alleviate their social anxiety.Read moreRead less
Longitudinal Communication Outcomes Following Traumatic Brain Injury
Funder
National Health and Medical Research Council
Funding Amount
$798,171.00
Summary
Traumatic brain injury (TBI) is the leading cause of disability in young Australians. The condition frequently manifests in impaired verbal communication. Communication is essential to successful rehabilitation, and return to society. However, the critical time for delivery of optimal treatment for communication remains unknown. This prospective longitudinal study will examine communication recovery following (TBI) to identify predictors of recovery and the best time to offer treatment.
Long Term Follow-up Of Two Randomised Controlled Trials Of Treatment For Depression And Alcohol-other Drug Comorbidity
Funder
National Health and Medical Research Council
Funding Amount
$252,925.00
Summary
This study proposes the long term follow-up of participants in two of the first and largest studies of psychological treatment for people with co-occurring depression and alcohol-other drug use problems ever conducted. This is a crucial next step in research on the effectiveness of psychological treatment among this highly prevalent yet often neglected section of the community.