Improving Treatment Strategies For Chronic Alphaviral Arthritic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$643,624.00
Summary
Chikungunya virus and Ross River virus cause epidemics of acute and chronic arthritic disease in humans, which is often poorly managed with current treatments. This grant seeks to understand the mechanisms that give rise to disease in order to identify improved treatment strategies. Both the persistence of viral replication in joint tissues and unnecessary inflammatory responses appear to be important factors driving chronic disease.
Driving Change: Using Emergency Department Data To Reduce Alcohol-related Harm
Funder
National Health and Medical Research Council
Funding Amount
$1,468,026.00
Summary
The proposed project is a system change within partner emergency departments, providing them the information and tools to act on both risky alcohol consumption in individual patients and the sources of alcohol in the community which cause the harm they experience. Most importantly, the proposed public health interventions act as a tool for emergency departments to regularly raise awareness with the public and policymakers regarding the impact of alcohol on patients, clinicians and hospitals.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100028
Funder
Australian Research Council
Funding Amount
$3,000,000.00
Summary
Australian Membership of the International Ocean Discovery Program. This proposal is for an 18-month membership of the International Ocean Discovery Program (IODP), the world’s largest collaborative research program in Earth and Ocean sciences. The Program studies the history and current activity of the Earth by conducting seagoing coring expeditions and monitoring of instrumented boreholes, using globally unique infrastructure that Australians would otherwise have no access to. Program outcomes ....Australian Membership of the International Ocean Discovery Program. This proposal is for an 18-month membership of the International Ocean Discovery Program (IODP), the world’s largest collaborative research program in Earth and Ocean sciences. The Program studies the history and current activity of the Earth by conducting seagoing coring expeditions and monitoring of instrumented boreholes, using globally unique infrastructure that Australians would otherwise have no access to. Program outcomes include understanding past global environmental change on multiple time scales, the deep biosphere, plate tectonics, formation and distribution of resources, and generation of hazards. These outcomes are paramount to Australia’s national science and research priorities, and societal and economic prosperity.Read moreRead less
A 140,000 year insight into the imprint of climate and humans on Australia. Before the arrival of Europeans, two events shaped Australia's current landscapes and biota more than any others: climate change during the glacial cycle and the arrival of humans on the continent. However, the full scale of these events is not well understood. High resolution analyses of two continuous 140 000 year old sediment deposits will be used in this project to fill this void and answer fundamental questions abou ....A 140,000 year insight into the imprint of climate and humans on Australia. Before the arrival of Europeans, two events shaped Australia's current landscapes and biota more than any others: climate change during the glacial cycle and the arrival of humans on the continent. However, the full scale of these events is not well understood. High resolution analyses of two continuous 140 000 year old sediment deposits will be used in this project to fill this void and answer fundamental questions about how current Australian environments came to be.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100067
Funder
Australian Research Council
Funding Amount
$10,000,000.00
Summary
Australian Membership of the International Ocean Discovery Program. Australian membership of the International Ocean Discovery Program:
This project is for a 5-year membership of the International Ocean Discovery Program, the world’s largest collaborative research program in earth and ocean sciences addressing international priorities. The program conducts seagoing coring expeditions and monitoring of instrumented boreholes to study the history and current activity of the Earth, recorded in sed ....Australian Membership of the International Ocean Discovery Program. Australian membership of the International Ocean Discovery Program:
This project is for a 5-year membership of the International Ocean Discovery Program, the world’s largest collaborative research program in earth and ocean sciences addressing international priorities. The program conducts seagoing coring expeditions and monitoring of instrumented boreholes to study the history and current activity of the Earth, recorded in sediments and rocks below the seafloor. The program’s aims include understanding past global environments on multiple time scales, the deep biosphere, plate tectonics, occurrence and distribution of resources, and generation of hazards. Several multinational expeditions are scheduled and planned in our marine jurisdiction and within the Australasian region. Read moreRead less
Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have change ....Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have changed over long periods of time is vital to understanding the nature of the system itself. The project intends to track changes in the diet of Adélie penguins from serially preserved ancient fecal (guano) remains dating back approximately 30,000 years. These remains are known to contain microscopic remnants of penguin prey.Read moreRead less
Predicting genetic exchange between species under climate change. This project aims to resolve the factors that lead to the mixing of species’ gene pools, with a focus on whether climate change will increase such mixing, possibly leading to extinction by genetic swamping.
The significance is that the project would improve our understanding of speciation and species’ vulnerability to rapid climate change through genetic mixing; a largely overlooked process.
Key outcomes would be to generate new k ....Predicting genetic exchange between species under climate change. This project aims to resolve the factors that lead to the mixing of species’ gene pools, with a focus on whether climate change will increase such mixing, possibly leading to extinction by genetic swamping.
The significance is that the project would improve our understanding of speciation and species’ vulnerability to rapid climate change through genetic mixing; a largely overlooked process.
Key outcomes would be to generate new knowledge of a fundamental evolutionary process and extend the toolbox of biodiversity managers facing rapid environmental change.
The project would benefit Australia by highlighting our unique biodiversity and scientific capability, and by training early career researchers in advanced evolutionary biology.Read moreRead less
U/Th dating of coral mortality and recovery rates in the Great Barrier Reef. This project aims to use high-efficiency U-Th geochronology and palaeoecology to identify past coral mortality events and community changes in the inshore Great Barrier Reef (GBR) and quantify subsequent recovery rates across a water quality gradient. These records will then be linked to natural and human impacts, especially since European settlement. The project outcomes will improve understanding of past disturbances ....U/Th dating of coral mortality and recovery rates in the Great Barrier Reef. This project aims to use high-efficiency U-Th geochronology and palaeoecology to identify past coral mortality events and community changes in the inshore Great Barrier Reef (GBR) and quantify subsequent recovery rates across a water quality gradient. These records will then be linked to natural and human impacts, especially since European settlement. The project outcomes will improve understanding of past disturbances and recovery rates in the GBR ecosystem and help focus management in the face of increased human pressure and environmental changes.Read moreRead less
Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess c ....Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess chemical fate on a national level by linking sales/use with fate and release from wastewater treatment plants and assess treatment efficiency at >100 plants around Australia. The project expects to provide insight for government, wastewater managers and industry into hazards that may affect environmental and human health.Read moreRead less
Parole in crisis? Public opinion on the use of parole. Serious crimes committed by parolees in Australia have brought parole into the public eye. Without concrete evidence, governments often act on the assumption that the public holds punitive attitudes. This project is expected to develop an evidence base to inform policy on parole at a crucial time when governments are under pressure to restrict its use. Three mixed-method studies aim to assess: what public views on parole are; why the public ....Parole in crisis? Public opinion on the use of parole. Serious crimes committed by parolees in Australia have brought parole into the public eye. Without concrete evidence, governments often act on the assumption that the public holds punitive attitudes. This project is expected to develop an evidence base to inform policy on parole at a crucial time when governments are under pressure to restrict its use. Three mixed-method studies aim to assess: what public views on parole are; why the public holds these views; and what influence these views have on policy and practice. The project is expected to make contributions to: creating information strategies that properly inform the public; supporting prisoner reintegration strategies; and shaping criminal justice policies based on informed community feedback.Read moreRead less