Measuring Patient Preferences For Treatment Of Colorectal Cancer Using Discrete Choice Modelling
Funder
National Health and Medical Research Council
Funding Amount
$188,912.00
Summary
Around the world, governments, medical professional bodies, individual clinicians and patients are trying to make decisions in health care more rationally. More of these decisions are 'informed' by evidence-based medicine, which depends on a systematic review of all relevant evidence of acceptable scientific rigour. This kind of systematic review has been conducted for the management of colorectal cancer. Patients making choices about possible treatment for colorectal cancer will then have the b ....Around the world, governments, medical professional bodies, individual clinicians and patients are trying to make decisions in health care more rationally. More of these decisions are 'informed' by evidence-based medicine, which depends on a systematic review of all relevant evidence of acceptable scientific rigour. This kind of systematic review has been conducted for the management of colorectal cancer. Patients making choices about possible treatment for colorectal cancer will then have the best 'evidence-based' information to hand. But not enough is known about what aspects of the treatment options matter most to patients. Choosing between different treatment options involves weighing up or trading-off different factors associated with each therapy. Depending on the clinical stage of their cancer, patients may have to choose between the type and size of surgical operation, whether or not to have chemotherapy and-or radiotherapy, the side effects of treatment, the chance of a recurrence of the disease and an early death as well as their quality of life. This research project will ask patients who have already been treated for their colorectal cancer what kind of tradeoffs they make between factors such as disease-free survival, toxicity of treatment and longer term quality of life. This will be done using hypothetical clinical scenarios comparing one type of treatment to another. In this way, the hypothetical choices will be informed by the patient's experience with treatment without asking them to reflect or dwell directly on their own treatment choices. The answers to the hypothetical choice questions can be used to assess what factors in treatment are most important to patients and by how much. This information can then be used by clinicians when presenting evidence-based information on treatment for patients newly diagnosed colorectal cancer.Read moreRead less
Neuronal Substrate Of Choice In The Rat Whisker System
Funder
National Health and Medical Research Council
Funding Amount
$405,851.00
Summary
Humans and other animals can optimise their goal-directed behaviour by linking stimuli or actions to consequent positive and negative rewards. How does an animal generate such associations, and make decisions in the natural environment where the associations are often uncertain, at times contradictory, and continuously changing? This project uses rat whisker system as an animal model to identify the neuronal basis of perceptual decision making and the role of context.
New Approaches To Describing And Valuing Quality Of Life
Funder
National Health and Medical Research Council
Funding Amount
$304,596.00
Summary
The ability of healthcare to improve quality of life is a major factor in determining public subsidy. This fellowship first explores patterns in Australian quality of life. This will identify groups with poor quality of life, and the remedying impact achieved under various interventions. It will then consider how people place value on aspects of quality of life. The two strands will allow linkage between important areas of quality of life and the policy impact of health interventions.
Resilient Democracy for the 21st Century. This project will establish novel foundational theoretical frameworks for the design of democratic institutions that can withstand internal and external pressure towards autocratisation. It will develop state of the art dynamic models of information manipulation and political dynamics, and analyse large-scale online survey experiments, as well as contemporary and historical data. This combination will deliver new insights into the management of sensitive ....Resilient Democracy for the 21st Century. This project will establish novel foundational theoretical frameworks for the design of democratic institutions that can withstand internal and external pressure towards autocratisation. It will develop state of the art dynamic models of information manipulation and political dynamics, and analyse large-scale online survey experiments, as well as contemporary and historical data. This combination will deliver new insights into the management of sensitive information and how to protect democracy from information manipulation. Ultimately, the project will generate a body of theoretical and empirical evidence for the design of more effective and resilient democratic institutions for a more inclusive economic development. Read moreRead less