Investigating Healing Outcomes In People With Venous Ulcers: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$340,834.00
Summary
Venous leg ulcers (VLU) are an extremely common, debilitating, costly problem and the burden is expected to rise with the ageing population, obesity and diabetes. Standard best practice treatment includes compression bandaging of the lower leg by tight bandaging. Application of 3 layer (3L) tubular bandage appears to be a promising new treatment according to a pilot study. We will conduct a randomised controlled trial to investigate improvement in healing with 3L and to measure cost-effectivenes ....Venous leg ulcers (VLU) are an extremely common, debilitating, costly problem and the burden is expected to rise with the ageing population, obesity and diabetes. Standard best practice treatment includes compression bandaging of the lower leg by tight bandaging. Application of 3 layer (3L) tubular bandage appears to be a promising new treatment according to a pilot study. We will conduct a randomised controlled trial to investigate improvement in healing with 3L and to measure cost-effectiveness when compared to standard compression.Read moreRead less
Clinical Effectiveness Of Aspirin In Healing Chronic Venous Leg Ulcers: A Randomised Double-blinded Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$791,980.00
Summary
Chronic venous leg ulcers (VLU) are a common and costly problem. People with chronic wounds found on the ankles and legs can be spontaneous or occur after minor trauma, they are often painful and ooze fluid. The burden is expected to rise with an ageing population and growing epidemic of diabetes and obesity which will increase challenges for clinicians. We will perform a clinical trial to see if aspirin plus 3 layer compression in people with venous leg ulcers heal more quickly.
Improving Asthma Control: General Practice Strategies To Optimise Medication Adherence
Funder
National Health and Medical Research Council
Funding Amount
$460,820.00
Summary
Asthma is a major health problem for Australia. Many patients have frequent symptoms and need urgent health care because they do not use a preventer inhaler regularly. This may be intentional e.g. fear of side-effects, and-or unintentional e.g. forgetting. This real-life study will test two simple strategies for GPs to improve their patients' use of preventer medications, to improve asthma control. Innovative technology will allow GPs to tailor the approach to each patient during a normal visit.
Glycan-glycan Interactions Between Bacterial Pathogens And Host Cells: A Novel Mechanism Of Bacterial Adherence, A New Opportunity For Strategies To Treat And Prevent Disease And A New Paradigm In Interactions Between Macromolecules.
Funder
National Health and Medical Research Council
Funding Amount
$1,059,344.00
Summary
Cell surface carbohydrates are ubiquitous throughout nature. Human cell surface carbohydrates are specifically targeted by microbial proteins. These interactions are crucial in causing disease. We have recently shown that the carbohydrates on our cells and those on pathogenic bacteria can interact with one another. Understanding the nature and role of these newly discovered interactions may lead to strategies to block them via new drugs and vaccines.
Increasing Engagement With Online Psychosocial Programs To Improve Mental Health In The Community
Funder
National Health and Medical Research Council
Funding Amount
$352,317.00
Summary
Online therapy programs have a strong evidence base in reducing mental health symptoms. However, take-up of these programs in the community is limited, and low adherence to these programs limits their impact. This project is a randomised controlled trial testing a novel approach to increasing uptake and adherence to psychosocial online programs, involving acceptance facilitation. Results will inform the dissemination of evidence-based psychosocial programs for a range of health conditions.
CareTrack Aged: Appropriate Care Delivered To Australians Living In Residential Aged Care
Funder
National Health and Medical Research Council
Funding Amount
$1,157,722.00
Summary
Given Australia’s rapidly ageing population, keeping up with future demands and maintaining quality of care in residential aged care facilities (RACF) is vital. This study will assess whether care delivered is consistent with the evidence in 15 conditions that are frequently managed in RACFs. These will include delirium, dementia, depression, pain management and medication management. We will also assess the quality of life of residents in RACFs.