Osteoporotic Fracture-Mortality Association And The Effect Of Anti-osteoporosis Treatment: A Multinational Study
Funder
National Health and Medical Research Council
Funding Amount
$84,800.00
Summary
Osteoporosis burden is due primarily to osteoporotic fractures resulting in economic and public health burden, increased disability, further fracture risk and more importantly early death. However, it remains under-treated although treatment reduces the number of fractures and may reduce early death. This study aims to understand which types of fractures result in early death and for which age groups and whether osteoporosis treatment does or does not reduce early death.
Prevention Of Multi-drug Resistant Tuberculosis In A High Prevalence Setting: ‘Connecting The DOTS’ In Vietnam
Funder
National Health and Medical Research Council
Funding Amount
$3,382,020.00
Summary
The close contacts of people with multi-drug resistant tuberculosis (MDR-TB) have a high risk of developing the disease. The V-QUIN MDR-TB Trial will evaluate the effectiveness of an oral antibiotic (levofloxacin) in preventing drug resistant TB among infected household contacts of TB patients. Household contacts from 10 Provinces in Vietnam will be randomly allocated to receive six-months of either levofloxacin or a placebo, and then followed for two years to see if they develop tuberculosis.
Testing And Treatment For Prostate Cancer In Australia: Epidemiology And Modelling
Funder
National Health and Medical Research Council
Funding Amount
$267,886.00
Summary
We aim to use observational data and mathematical modelling to investigate testing and treatment for prostate cancer in Australia. We will incorporate changes in prostate-specific antigen (PSA) testing and in clinical practice to investigate: a) over-diagnosis, being cancer cases diagnosed through PSA testing that would not have been otherwise diagnosed; b) the effect of PSA testing on prostate cancer mortality; and c) mortality and health care use under different PSA test scenarios.
Who To Treat, When To Treat And How To Treat Prostate Cancer: Generating Evidence To Guide Prostate Cancer Treatment Decisions
Funder
National Health and Medical Research Council
Funding Amount
$408,768.00
Summary
There is considerable uncertainty about which treatments lead to better outcomes for men with prostate cancer and whether treatment is always necessary. This project will compare different treatment options for prostate cancer, including active surveillance, to determine which offers the best chance of survival and least harm to men’s physical and mental wellbeing. It will also explore whether some men who do not receive active treatment (healthy older men) would benefit if they did.
Bariatric Surgery In Tasmania: Investigating Health Service Use, Costs, Patient Outcomes And Policy Options
Funder
National Health and Medical Research Council
Funding Amount
$667,655.00
Summary
About 1 in 20 Tasmanians are severely obese. Bariatric surgery can improve health for individuals with severe obesity but access to surgery is poor for most public patients. This study will investigate the pathways of patients referred for bariatric surgery in the Tasmanian public and private hospital systems to better understand the demand for surgery, the health outcomes, and costs associated with these different pathways. The findings will inform public policy and resource allocation.
Translating Gene Discovery For Key Diseases Into Clinical Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$772,490.00
Summary
The goal of the fellowship is capitalize on successful gene mapping studies for endometriosis, inflammatory bowel disease (IBD), melanoma and other complex diseases and conduct functional studies, cross-disease analyses, and genetic studies of response to treatment. These studies will identify specific genes responsible for increased disease risk to understand the biology of these diseases, their relationship with other diseases, and help improve disease management and clinical outcomes.