Reprogramming Of Ataxia Telangiectasia Fibroblasts To Generate IPS Cells
Funder
National Health and Medical Research Council
Funding Amount
$601,386.00
Summary
Ataxia telangiectasia (A-T) is a human genetic disorder characterised by immunodeficiency, cancer predisposition and neurodegeneration. The aim of this project is to generate adult stem cells from A-T patient as a model system to investigate the nature of the nervous system defect in this disorder. These adult stem cells will be employed to produce neuronal cells which will be a resource for screening for therapeutic compounds to treat A-T patients.