I am a physiologist investigating the role of molecular rhythmicity in physiological systems. My work focuses on the impact of disrupted rhythmicity on metabolism, cancer and fertility at the cellular level and is of particular importance when considering
The cell types of the blood, such as red and white blood cells, are produced in the bone marrow from a rare stem cell. The stem cell uses a handful of important master-regulatory genes that act in a hierarchy to promote the blood cell differentiation process. This research aims to understand how these master-regulators function in isolation and together in producing the white blood cells that are required for our immune response to microbes, vaccination and to prevent cancer.