Low Cost High Precision Radiotherapy: A Synergistic Framework For Tumour Tracking During Treatment
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Advances in technology have enabled radiotherapy to become more sophisticated and more efficient at treating cancer. Yet, despite its sophistication, today radiotherapy suffers from a major problem: whilst we routinely image patients prior to treatment, no anatomical information is available during treatment. This project aims to solve this problem by making use of a number of sensors that are already available in a radiotherapy to track the tumours positions during treatment, when it counts.
Real-time In-vivo Imaging During Lung Cancer Radiotherapy
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Lung tumours move in clinically significant and unpredicable ways. Current radiotherapy is limited by the lack of real-time imaging to monitor tumour motion. The aim of this project is to develop and clinically implement Real-time In-vivo Imaging to enable motion-adaptive radiotherapy and thereby improve treatment outcomes. Real-time In-vivo Imaging is a software technology that will be applicalbe to 90% of modern radiotherapy systems globally and will enable wide access to advanced cancer care.
Development Of A Chronically Implantable, Miniaturised Device For Monitoring Ventricular Function, To Assist Tracking An
Funder
National Health and Medical Research Council
Funding Amount
$335,000.00
Summary
Heart failure (HF) is increasing - with ~5million sufferers (1-3rd in New York Heart Association Class III-IV i.e. severe cases) in the US alone, and ~12-15 million worldwide. Its management consumes health resources and strains sufferers, families and institutions. The proposed monitoring-management device, chronically implanted by minimally invasive surgery, will track the heart’s pumping pattern. It will allow informed decisions to optimise therapy, thereby improving Quality of Life (QOL), de ....Heart failure (HF) is increasing - with ~5million sufferers (1-3rd in New York Heart Association Class III-IV i.e. severe cases) in the US alone, and ~12-15 million worldwide. Its management consumes health resources and strains sufferers, families and institutions. The proposed monitoring-management device, chronically implanted by minimally invasive surgery, will track the heart’s pumping pattern. It will allow informed decisions to optimise therapy, thereby improving Quality of Life (QOL), decreasing hospitalisations and decreasing healthcare costs. We aim to develop a small, chronically and easily implantable device to track changes in heart function in HF patients.Read moreRead less
A Motion Correction Technique For Accurate PET/CT Brain Imaging In Paediatric And Dementia Patients
Funder
National Health and Medical Research Council
Funding Amount
$190,450.00
Summary
PET-CT imaging is a vital tool in the diagnosis and management of patients with brain disorders including dementia, epilepsy and cancer. However images are often distorted by patient motion, particularly in demented and paediatric patients. The CI has recently developed a motion tracking and correction method to derive images nearly free of motion effects. This aim of this project is to evaluate its impact on image quality in a variety of patients referred for PET- CT brain investigations.
Neural Plasticity Following Lesions Of The Central Nervous System In Multiple Sclerosis
Funder
National Health and Medical Research Council
Funding Amount
$523,487.00
Summary
The brain and nervous system can adapt to injury and disease. The compensatory changes underlying this plasticity can ameliorate disability. This project will investigate the underlying mechanisms in patients with multiple sclerosis, by examining changes in the properties of nerve fibres in the peripheral nerve. The rationale for the project is that the properties of peripheral nerve fibres can reflect, at least in part, the properties of their cell bodies within the spinal cord.