Smart Hybrid Material For Cartilage Tissue Engineering
Funder
National Health and Medical Research Council
Funding Amount
$299,564.00
Summary
Tissue engineering is a promising approach to repair damaged/degenerated cartilage caused by various diseases or injuries. Because of its limited capacity for self repair cartilage becomes a constriant to normal everyday life once degenerated. This project aims to develop composite polymers for cartilage repair. The potential of this newly developed material for cartilage tissue engineering will be investigated through the material and biological characterisation techniques.
Biothermosetting Bone Filler: An Injectable Osteoconductive Repair Material
Funder
National Health and Medical Research Council
Funding Amount
$601,698.00
Summary
Bone injury is a common and profoundly debilitating issue, and is responsible for extended partial or complete loss of mobility and associated economic impact during slow healing. There is strong demand for technology that reduces the time taken for bone repair. There is still a paucity of clinically effective biocompatible materials for treatment. We have developed a novel approach for a thermoresponsive hydrogel with unique properties suitable for rapid bone filling and regeneration.
Functional Nano-cement Scaffolds For The Treatment Of Osteoporotic Bone Defects
Funder
National Health and Medical Research Council
Funding Amount
$408,768.00
Summary
Osteoporosis affects 1.2 million Australians and will cost $33.6 billion by 2022. This study aims to develop a novel nano-cement platform for custom-designed bone repair in osteoporosis, by using purpose-designed nanomaterials and advanced 3D printing technique. The research findings will lead to the development of a new bone repair strategy, expand knowledge on both biomaterials engineering and osteoporosis treatment, and improve the quality of life of Australians.
Development Of Gene-activated Scaffolds As Bone Bioreactor For Bone Regeneration And Osteointegration
Funder
National Health and Medical Research Council
Funding Amount
$215,100.00
Summary
The worldwide market for bone substitutes has been estimated at over US $1 billion annually. The emerging technology of cell based therapy has opened a new window for the treatment of bone defects. This project is to develop gene-activated scaffolds able to induce blood vessel formation thus improving the local nutrition supply, and subsequently stimulating bone formation in bone defects, as well as osteointegration around implant surface. The knowledge generated from this project will help the ....The worldwide market for bone substitutes has been estimated at over US $1 billion annually. The emerging technology of cell based therapy has opened a new window for the treatment of bone defects. This project is to develop gene-activated scaffolds able to induce blood vessel formation thus improving the local nutrition supply, and subsequently stimulating bone formation in bone defects, as well as osteointegration around implant surface. The knowledge generated from this project will help the treatment of a number of orthopaedic and dental conditions.Read moreRead less
A Novel Strategy For The Treatment Of Chronic Skeletal Joint Defects
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Skeletal joint injuries often heal poorly with current treatment approaches and lead to the onset of osteoarthritis. This project will produce a synthetic graft with unique properties to mimic the complex structure of joint tissues, and high bioactivity to induce optimal healing of the joint. This graft will constitute a viable alternative for the treatment of skeletal joint defects, resulting in significant healthcare benefits and improved long-term outcomes.
Pre-clinical Validation Of A Novel Implant For Bone Tissue Engineering
Funder
National Health and Medical Research Council
Funding Amount
$435,767.00
Summary
The aim of this grant to was examine a new method for manufacturing implants to improve repair of critical bone defects. It involves new technology for the manufacture of porous scaffolds and testing their delivery in a biological, bone repair setting.
Novel Strategy For The Treatment Of Large Bone Defects Using A Unique Biomaterial With Tailored Microstructure
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
There is a rapidly increasing and pressing medical need for the development of synthetic implants that can regenerate large amounts of lost or diseased bone. This project will produce a unique implant with optimal mechanical and biological performance, which represents a viable alternative to bone grafting with broad applications for the repair of large or challenging bone defects. Such an achievement will produce significant healthcare benefits and improved long-term outcomes.
Special Research Initiatives - Grant ID: SR0354535
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Advanced Electromaterials from Nanomaterials and Biomaterials. The proposed initiative brings together relevant sectors of the nanomaterials, biomaterials and electrochemistry research communities. It is envisaged that the collective complementary expertise will give rise to research opportunities and insights into the emerging work of electro-bio-nano. Scientific and technological challenges that exist in this multidiscipline research space include areas as diverse as the development of more ....Advanced Electromaterials from Nanomaterials and Biomaterials. The proposed initiative brings together relevant sectors of the nanomaterials, biomaterials and electrochemistry research communities. It is envisaged that the collective complementary expertise will give rise to research opportunities and insights into the emerging work of electro-bio-nano. Scientific and technological challenges that exist in this multidiscipline research space include areas as diverse as the development of more efficient nerve cell communication implants, understanding and control of biocorrosion/biofouling and the use of biomimicry to produce more efficient catalysts and artificial muscles.Read moreRead less
ARC Centre for Nanostructured Electromaterials. Electromaterials transport electrons or ions and facilitate charge transfer, underpinning most energy capture/storage processes and cell communication. We propose a national Centre to develop nanostructured electromaterials with exceptional properties. The Centre aims to synthesise novel nanomaterials and assemble them into innovative nanoscale devices. We will exploit these materials to enhance performance in energy conversion/storage systems (eg. ....ARC Centre for Nanostructured Electromaterials. Electromaterials transport electrons or ions and facilitate charge transfer, underpinning most energy capture/storage processes and cell communication. We propose a national Centre to develop nanostructured electromaterials with exceptional properties. The Centre aims to synthesise novel nanomaterials and assemble them into innovative nanoscale devices. We will exploit these materials to enhance performance in energy conversion/storage systems (eg. photovoltaics, batteries, including wearable systems), and novel energy transfer in bioapplications (eg. Bionic Ear). These advances, together with the resource of trained personnel, will assist Australian industry to exploit this exciting area.Read moreRead less