We have discovered a single tumour factor which causes cancer cachexia, a wasting condition that is one of the worst complications of malignancy, for which there is no current effective treatment. We have developed antibodies which effectively block this condition in preclinical models and have produced human/humanised version of this. This application is to characterise these human antibodies to allow us proceed to clinical trials.
Sexual well-being and ageing: a study of older Australian women. This research addresses important issues of ageism and sexism that together affect older women's health and well-being. The findings will inform the link between aging, sexuality and more general dimensions of health and well-being and advance our understanding of issues central to policy and services for older Australians.
Improving Australia's response to childhood obesity: prevention education and its impact on mothers and families. This project will generate new and more considered approaches to childhood obesity prevention, and in turn ensure future investment of public funds in this area best supports children's health.
Mapping the connectome that controls blood pressure. The connections that an individual brain cell receives from other cells ultimately determines its behaviour. Using a revolutionary new technique, the project will create a map of the brain cells that control blood pressure.
Industrial Transformation Training Centres - Grant ID: IC170100022
Funder
Australian Research Council
Funding Amount
$4,420,408.00
Summary
ARC Training Centre for Innovative BioEngineering. The ARC Training Centre for Musculoskeletal Biomedical Technologies will provide the next-generation of skilled graduates to overcome industry-focused challenges in musculoskeletal regeneration. The Centre expects to engineer a set of integrated technologies to personalise implants for the unique biological, physical and lifestyle characteristics of the recipient. Expected outcomes of the Centre include embedded bioelectronic sensors to assess a ....ARC Training Centre for Innovative BioEngineering. The ARC Training Centre for Musculoskeletal Biomedical Technologies will provide the next-generation of skilled graduates to overcome industry-focused challenges in musculoskeletal regeneration. The Centre expects to engineer a set of integrated technologies to personalise implants for the unique biological, physical and lifestyle characteristics of the recipient. Expected outcomes of the Centre include embedded bioelectronic sensors to assess and optimise the healing process. In addition, the Centre will produce data for use in deriving the next-generation of implants, giving rise to improved health outcomes, economic benefits, and a skilled workforce able to advance and perpetuate this important field.Read moreRead less
Reducing health disparities for older LGBTI Australians. Reducing health disparities for older LGBTI Australians. This project aims to optimise health and aged care services throughout Australia, by bringing together researchers and key organisations in the health, aged, and lesbian, gay, bisexual, transgender and intersex (LGBTI) sectors to build a much-needed evidence base. Older LGBTI Australians have vastly poorer health outcomes than the broader population. This project will provide detaile ....Reducing health disparities for older LGBTI Australians. Reducing health disparities for older LGBTI Australians. This project aims to optimise health and aged care services throughout Australia, by bringing together researchers and key organisations in the health, aged, and lesbian, gay, bisexual, transgender and intersex (LGBTI) sectors to build a much-needed evidence base. Older LGBTI Australians have vastly poorer health outcomes than the broader population. This project will provide detailed quantitative and qualitative data on the challenges and needs of older LGBTI Australians and service providers, and develop essential resources so policymakers and service providers can reduce older LGBTI Australians’ health disparities.Read moreRead less
Drug using behaviours and beliefs, and associated harms, among gay and bisexual men. Gay and bisexual men have high rates of drug use. This cohort study will contribute to Australia’s response to drug use by identifying: risk factors for, and prevalence and incidence of, drug use and associated harms within this high risk population; the role of gay community norms in individuals' beliefs about and motivations for drug use; and, implications for HIV and HCV infection. The findings will help to b ....Drug using behaviours and beliefs, and associated harms, among gay and bisexual men. Gay and bisexual men have high rates of drug use. This cohort study will contribute to Australia’s response to drug use by identifying: risk factors for, and prevalence and incidence of, drug use and associated harms within this high risk population; the role of gay community norms in individuals' beliefs about and motivations for drug use; and, implications for HIV and HCV infection. The findings will help to better target, educate and support those at risk of drug use and associated harms. Read moreRead less
Superbugs and veterinary drugs: are multidrug-resistant zoonotic pathogens residing in Australian animals? Antibiotic resistance is a growing problem affecting human health that is now emerging in animals and veterinary hospitals. This project will integrate surveillance with novel treatments and preventatives to develop effective strategies to limit the impact of resistant bacteria to animal health and prevent transfer between humans and animals.
Partner choice and sexual behaviour among gay and bisexual men. Current social and political debate about what constitutes legitimate relationships hinge on the status of same-sex relationships. Partner choice is key to understanding individuals' sexual behaviour and the relationships they develop in response. Yet gay and bisexual men's (GBM) sexual partner choices have not been researched. The project aims to describe types of partner choices among GBM and how these affect the specific sex prac ....Partner choice and sexual behaviour among gay and bisexual men. Current social and political debate about what constitutes legitimate relationships hinge on the status of same-sex relationships. Partner choice is key to understanding individuals' sexual behaviour and the relationships they develop in response. Yet gay and bisexual men's (GBM) sexual partner choices have not been researched. The project aims to describe types of partner choices among GBM and how these affect the specific sex practices, including risk behaviours, in which they engage and their style and pattern of relationships. It also aims to identify the contextual and individual factors associated with these choices. This evidence is expected to inform current debate and help improve health promotion and relationship support work among GBM.Read moreRead less
Muscling Up: Australian men, sexualisation and body image enhancment. Australian men are under increasing pressure to appear fit, with psychologists and others identifying body dissatisfaction, depression, and illegal supplement use as evidence of a 'crisis'. However, no research has explored men's emotional and physical investments in injunctions to be 'healthy', or relatively new opportunities in consumer culture for men to style the body. This qualitative project aims to explore men's motivat ....Muscling Up: Australian men, sexualisation and body image enhancment. Australian men are under increasing pressure to appear fit, with psychologists and others identifying body dissatisfaction, depression, and illegal supplement use as evidence of a 'crisis'. However, no research has explored men's emotional and physical investments in injunctions to be 'healthy', or relatively new opportunities in consumer culture for men to style the body. This qualitative project aims to explore men's motivations for engaging in body image-enhancing practices. It expects to provide insight that will benefit those engaged in advocating healthy lifestyles to men.Read moreRead less