Optimising disease surveillance to support decision-making. COVID-19 has demonstrated the critical role of epidemic data and analytics in guiding government response to pandemic threats, reducing disease and saving lives. The demand for epidemic analytics for response to threats of national significance will only grow. The goals of this project are to 1) determine the combination(s) of surveillance methods that provide the most useful data for epidemic analysis and 2) translate these findings in ....Optimising disease surveillance to support decision-making. COVID-19 has demonstrated the critical role of epidemic data and analytics in guiding government response to pandemic threats, reducing disease and saving lives. The demand for epidemic analytics for response to threats of national significance will only grow. The goals of this project are to 1) determine the combination(s) of surveillance methods that provide the most useful data for epidemic analysis and 2) translate these findings into the blueprint for a next-generation infectious disease surveillance system for Australia. We will use a simulation-evaluation approach, coupling methods from infectious disease modelling with those from information theory optimal design. Outcomes will enable more tailored and effective pandemic response.Read moreRead less
Increasing the effectiveness of remote and cross-cultural collaborations in organisations. Minerals, oil and gas exports dominate the Australian economy, and the effective organisation and management of collaborative work spanning remote, dispersed, environmentally fragile and culturally sensitive locations in this industry is a key challenge. Findings will provide insight into the systems, processes, and skills that are required to collaborate in these domains, improving international competiti ....Increasing the effectiveness of remote and cross-cultural collaborations in organisations. Minerals, oil and gas exports dominate the Australian economy, and the effective organisation and management of collaborative work spanning remote, dispersed, environmentally fragile and culturally sensitive locations in this industry is a key challenge. Findings will provide insight into the systems, processes, and skills that are required to collaborate in these domains, improving international competitiveness and global impact. Extensive efforts to interpret, synthesize and disseminate findings for scholars and non-scientists will also help inform educational agendas within industry and higher education to better prepare future collaborators.Read moreRead less
Country practices: an analysis of factors affecting the wellbeing of general practitioners and their families in rural and remote WA. This project will analyse relationships between (1) the shortage of general practitioners in rural and remote Western Australia and (2) the wellbeing of practitioners and their families. The study will use an appropriate sociological framework, together with data drawn primarily from participant observation and intensive interviewing. It will deepen our understand ....Country practices: an analysis of factors affecting the wellbeing of general practitioners and their families in rural and remote WA. This project will analyse relationships between (1) the shortage of general practitioners in rural and remote Western Australia and (2) the wellbeing of practitioners and their families. The study will use an appropriate sociological framework, together with data drawn primarily from participant observation and intensive interviewing. It will deepen our understanding of problems in attracting and retaining general practitioners to work in rural and remote communities, and of ways in which these problems might be addressed. Innovative aspects of the study include the use of ethnographic research methods and the inclusion of family members in the analysis.Read moreRead less
Magnetically controlled drug release from tissue scaffolds for the treatment of acute burns. Severe skin burns are frequently associated with functionally disabling scarring and the risk of death. New magnetically activated wound seals for the treatment of acute burns will be developed that reduce the need for frequent painful dressing changes and hence facilitate rapid healing with a significantly reduced chance of scarring.
Unravelling The Mechanism Of MHC Class-I Associated Drug Hypersensitivities
Funder
National Health and Medical Research Council
Funding Amount
$566,308.00
Summary
Some drugs cause adverse reactions that are life threatening. We think these reactions are mediated by killer T cells as they are genetically controlled by immune response genes that normally guide immunity to microbes. We will study immune reactions to the drug abacavir, used to treat HIV (AIDS); allopurinol used to prevent gout and carbamazepine, used to treat epilepsy. The study may also help devise better treatments for patients who experience severe forms of these reactions.
How migration reshapes labour markets: a study of professional service firms. Australia needs skilled migration to maintain its economic growth and replenish its skill base as the population ages. It needs the skills of migrant accountants. This project will identify the barriers migrants face when seeking work in the financial services industry and discover how migration is changing the financial services labour market.
The entrainment of circadian rhythms in marsupial mammals: behavioural and sub-cellular investigation of non-rod, non-cone ocular photoreceptors. Our investigation will provide a contribution to understanding the role that photoreceptors play in the mechanisms that control circadian rhythms and will ultimately lead to a better understanding of the basic physiology of sleep and circadian cycles, their contribution to learning and memory and their impact on waking performance. Targeted drug develo ....The entrainment of circadian rhythms in marsupial mammals: behavioural and sub-cellular investigation of non-rod, non-cone ocular photoreceptors. Our investigation will provide a contribution to understanding the role that photoreceptors play in the mechanisms that control circadian rhythms and will ultimately lead to a better understanding of the basic physiology of sleep and circadian cycles, their contribution to learning and memory and their impact on waking performance. Targeted drug development and the design of lighting systems effective in regulating circadian rhythms will improve the quality of life and competitiveness of the many citizens who endure abnormal sleep/wakefulness schedules.Read moreRead less
Analysis and modeling of driving patterns for limited-range electric vehicles. The electrification of the personal transport sector seems to be only a matter of time. It is important to study and model the effects of this sector now, in order to recommend decision makers on issues like standardization and infrastructure planning. Understanding and being able to predict EV driving and charging patterns will allow us to provide planning assistance for:
· Effects of day-time dependent energy pri ....Analysis and modeling of driving patterns for limited-range electric vehicles. The electrification of the personal transport sector seems to be only a matter of time. It is important to study and model the effects of this sector now, in order to recommend decision makers on issues like standardization and infrastructure planning. Understanding and being able to predict EV driving and charging patterns will allow us to provide planning assistance for:
· Effects of day-time dependent energy pricing structure on EV charging behavior
· Optimal energy pricing to encourage off-peak charging
· Optimal number and location of EV charging stations
· Expected uptake of PHEV/EVs depending on petrol, electricity and conversion cost
· Expected additional energy demand for EVs and PHEVs with day-time energy usage pattern
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Innovative approaches to understanding and limiting the public health risks of Cryptosporidium and Giardia in animals in Australian catchments. Sophisticated molecular typing and modelling will be used to determine if chlorine-resistant parasites in animals in catchments are responsible for infection in humans. Improved catchment management and risk mitigation strategies will be developed during this project, which will make a substantial contribution to the provision of safe drinking water acro ....Innovative approaches to understanding and limiting the public health risks of Cryptosporidium and Giardia in animals in Australian catchments. Sophisticated molecular typing and modelling will be used to determine if chlorine-resistant parasites in animals in catchments are responsible for infection in humans. Improved catchment management and risk mitigation strategies will be developed during this project, which will make a substantial contribution to the provision of safe drinking water across Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101520
Funder
Australian Research Council
Funding Amount
$375,573.00
Summary
Work fragmentation in the gig economy. The gig economy has fragmented working arrangements in Australia and globally, disrupting how, where and on what terms work is performed. This study will systematically interrogate the consequences for work and workers in Australia of the growth and diversification of gig work. It will use a labour geography approach to explain how workers navigate working in the gig economy in the context of their wider lives. This will extend existing research by groundin ....Work fragmentation in the gig economy. The gig economy has fragmented working arrangements in Australia and globally, disrupting how, where and on what terms work is performed. This study will systematically interrogate the consequences for work and workers in Australia of the growth and diversification of gig work. It will use a labour geography approach to explain how workers navigate working in the gig economy in the context of their wider lives. This will extend existing research by grounding analysis in the lived experience of workers both across various segments of the gig economy and over time. The project will extend academic theory and provide guidance to policymakers as to how to harness the benefits of gig work while mitigating potential harm.Read moreRead less